超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
一个色亚洲,亚洲av无码无线在线观看,小婕子伦流澡到高潮H
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CD299/Cy5.5 Conjugated antibody (bs-10064R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-10064R-Cy5.5
英文名稱 Rabbit Anti-CD299/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的CD299抗體
別    名 C type lectin domain family 4 member M; C type lectin domain family 4, member M; C-type lectin domain family 4, member M; CD209 antigen like protein 1; CD209 antigen-like; CD209L; CD209L1; CD299 antigen; CLEC4M; DC SIGN related protein; DC SIGN2; DC SIGNR; DC-SIGN related protein; DC-SIGN2; DC-SIGNR; DCSIGN-related protein; DCSIGNR; dendritic cell specific ICAM-3-grabbing nonintegrin 2; Dendritic cell-specific ICAM-3-grabbing non-integrin 2; HP10347; L SIGN; Liver/lymph node specific ICAM 3 grabbing nonintegrin; Liver/lymph node-specific ICAM3-grabbing nonintegrin; LSIGN; Mannose binding C-type lectin DC-SIGNR; MGC129964; MGC47866; CLC4M_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CD299
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Dendritic cells (DC) play a primary role in the immune system as antigen presenting cells. A key molecule, dendritic cell specific ICAM3 grabbing nonintegrin (DC SIGN1), is involved in regulating interactions between DC and resting T cells, including antigen presentation to T cells and enhancement of transinfection of CD4+ T cells by HIV 1. Efforts to identify additional type II membrane proteins resulted in the isolation of a related molecule named CD299, also known as DC SIGNR (DC SIGN Related), DC SIGN2, CD209L, and L SIGN (liver/lymph nodespecific ICAM3 grabbing nonintegrin). CD299 is located on Human chromosome 19p13.3 and shares 73-80% amino acid identity with DC SIGN1. Its structure is similar to DC SIGN1 and therefore binds mannose residues in a calcium dependent fashion, including ICAM3 and HIV 1 gp120. CD299 is polymorphic, since allelic variations of the exon 4 encoded sequence have been isolated. This is further supported by a study demonstrating the ability to isolate a large repertoire of CD299 transcripts largely the result of alternative splicing of the 7 coding exons. CD299 is primarily transcribed in the liver and lymph nodes but not in monocyte derived DC. Expression of CD299 is restricted to endothelial cells derived from liver sinusoids, lymph nodes sinuses, and capillaries, although variable expression in placenta and some monocytic cell lines has also been reported, including both membrane and soluble isoforms of the protein.

Function:
Probable pathogen-recognition receptor involved in peripheral immune surveillance in liver. May mediate the endocytosis of pathogens which are subsequently degraded in lysosomal compartments. Probably recognizes in a calcium-dependent manner high mannose N-linked oligosaccharides in a variety of pathogen antigens, including HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus protein S. Is a receptor for ICAM3, probably by binding to mannose-like carbohydrates. Is presumably a coreceptor for the SARS coronavirus.

Subunit:
Homotetramer. Binds to many viral surface glycoproteins such as HIV-1 gp120, HIV-2 gp120, SIV gp120, ebolavirus glycoproteins, HCV E2, and human SARS coronavirus S protein.

Subcellular Location:
Isoform 1, 2, 3: Cell membrane; Single-pass type II membrane protein (Potential). Isoform 5, 6, 7, 10: Secreted (Potential).

Tissue Specificity:
Predominantly highly expressed in liver sinusoidal endothelial cells and in lymph node. Found in placental endothelium but not in macrophages. Expressed in type II alveolar cells and lung endothelial cells.

Similarity:
Contains 1 C-type lectin domain.

Database links:

Entrez Gene: 10332 Human

Omim: 605872 Human

SwissProt: Q9H2X3 Human

Unigene: 421437 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久99影院| 国内少妇BBWBBw黑森林 | 亚洲精品国产一区二区 | 看色网站 | WWW片香蕉内射在袋88AV8 | 久久青草网站 | 把护士强奷到舒服的动态图 | 日韩视频在线免费观看 | 国产视频一区二区三区在线播放 | 一本色道久久综合狠狠躁的推荐 | 拍拍拍av| 一本一本久久aa综合精品 | 欧美性猛交xxxx乱大交久久 | www.亚洲国产 | 国产在线99 | 天天干天天做 | 777亚洲熟妇自拍无码区 | 黄色工厂这里只有精品 | 国产丝袜无码免费视频 | 毛茸茸xxxx毛茸茸 | 九九精品超级碰视频 | 影音先锋人妻每日资源站 | 色678黄网全部免费 国产精彩视频 | 在线精品视频免费观看 | 天堂资源在线官网 | 啦啦啦www在线观看免费视频 | 老熟女高潮一区二区三区 | 少妇挑战三个黑人惨叫4p国语 | 国产欧美久久久久久 | 51视频国产精品一区二区 | 久久精品二区三区 | 久久天天免费天天免费 | 国产成人无码AV在线影院 | 日本三级全黄三级a | 国产精品久久久久久成人 | 国产成人无码精品一区在线观看 | 亚洲欧洲日产国码高潮 | 麻豆传媒影视 | 欧美一区二区三区四区视频 | caoporm国产精品视频免费 | 99插插|