超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩视频中文字幕精品偷拍,人妻少妇偷人精品视频,五月色夜婷婷丁香琪琪
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HECW1/AP Conjugated antibody (bs-11692R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11692R-AP
英文名稱 Rabbit Anti-HECW1/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的肌萎縮側索硬化癥相關蛋白HECW1抗體
別    名 NEDL1; C2 and WW domain-containing protein 1; E3 ubiquitin-protein ligase HECW1; HECT; HECT type E3 ubiquitin ligase; HECT, C2 and WW domain containing E3 ubiquitin protein ligase 1; HECT, C2 and WW domain-containing protein 1; HECW 1; Hecw1; HECW1_HUMAN; hNEDL1; NEDD4 like ubiquitin protein ligase 1; NEDD4-like E3 ubiquitin-protein ligase 1; NEDL-1; NEDL 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  細胞凋亡  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, )
產品應用 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 179kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HECW1 (251-350aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品介紹 background:
NEDL1 is a 1,606 amino acid cytoplasmic protein predominantly expressed in neurons of adult and fetal brain. NEDL1 functions as an E3 ubiquitin-protein ligase that, characteristic of E3 ligase proteins, accepts ubiquitin (in the form of a thioester) from an E2 ubiquitin-conjugating enzyme and transfers that ubiquitin residue to substrates targeted for degradation. NEDL1 mediates ubiquitination and subsequent degradation of Dvl-1 and targets mutant SOD-1. NEDL1 forms cytotoxic aggregates with Dvl, TRAP-?and mutant SOD1 that lead to motor neuron death in FALS (familial amyotrophic lateral sclerosis). individuals affect by FALS (also known as Lou Gehrig's disease) experience muscle weakness and atrophy throughout the body. FALS is caused by the degeneration of upper and lower motor neurons resulting in loss of signal to muscles.

Function:
E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent degradation of DVL1. Also targets the mutant SOD1 protein involved in familial amyotrophic lateral sclerosis (FALS). Forms cytotoxic aggregates with DVL1, SSR3 and mutant SOD1 that lead to motor neuron death in FALS.

Subunit:
Interacts with DVL1 and SSR3. Also interacts with mutant SOD1.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Predominantly expressed in neurons of adult and fetal brain. Weakly expressed in the kidney.

Similarity:
Contains 1 C2 domain.
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 2 WW domains.

Database links:

Entrez Gene: 23072 Human

Omim: 610384 Human

SwissProt: Q76N89 Human

Unigene: 164453 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久精品一区二区三区日韩 | 欧洲尺码日本尺码专线不卡顿 | 欧美伊人精品成人久久综合97 | 色婷婷精品久久二区二区我来 | 日本高清视频xxxxx | 欧美日韩高清一区 | 欧美一区二区视频17c | 国内精品视频一区二区三区八戒 | 被仇人调教成禁脔h虐莫 | 7788成人免费播放网站 | 午夜国产情侣在线播放 | 亚洲综合一页 | 奇色影视| 久久久一牛精品99久久精品66 | 色老综合老女人久久久 | 免费国产高清在线精品一区 | 任你躁一区二区久久99 | 亚洲不卡一区二区三区 | 91麻豆国产福利在线观看宅福利 | 四虎永久在线精品免费A | 男女啪啪免费观看无遮挡 | 国产户外野战AV一级 | 91传媒麻豆激情在线观看 | 九九国产精品无码免费视频 | 久久国产在线视频 | 免费黄色网页在线观看 | 成年网站在线免费观看 | 国产69视频在线观看 | 日本在线高清 | 成人av一区二区在线观看 | 东京热无码AV在线 | 欧洲精品成人免费视频在线观看 | 久久久免费在线观看 | 亚洲国产超清无码专区 | 黄色片免费网站 | 超碰99久久 | 国产成人动漫 | 老司机深夜福利视频 | 欧洲乱码专区网站 | 国产亚洲精品久久久久的角色 | 国产精品无码久久AⅤ人妖 秋霞av国产精品一区 |