超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
狠狠干天天爽,亚洲第一久久久,青青久久久久
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ChRM2/FITC Conjugated antibody (bs-0236R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0236R-FITC
英文名稱 Rabbit Anti-ChRM2/FITC Conjugated antibody
中文名稱 FITC標記的毒蕈堿型乙酰膽堿受體抗體
別    名 7TM receptor; Acetylcholine receptor, muscarinic, 2; Acm2; Cholinergic receptor muscarinic 2; Cholinergic receptor, muscarinic 2, cardiac; Cholinergic receptor, muscarinic 2, isoform a; Cholinergic receptor, muscarinic 2a; Cholinergic receptor, muscarinic 2, isoform a; CHRM 2; CHRM2; chrm2a; CM2; FLJ43243; HM 2; HM2; M2; M2 muscarinic receptor; MGC120006; MGC120007; ACM2_HUMAN; Muscarinic acetylcholine receptor M2; Muscarinic M2 receptor; Acetylcholine receptor(M2).  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  細胞膜受體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Chicken, Pig, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ChRM2 C-terminus
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The muscarinic cholinergic receptors belong to a larger family of G protein-coupled receptors. The functional diversity of these receptors is defined by the binding of acetylcholine to these receptors and includes cellular responses such as adenylate cyclase inhibition, phosphoinositide degeneration, and potassium channel mediation. Muscarinic receptors influence many effects of acetylcholine in the central and peripheral nervous system. The muscarinic cholinergic receptor 2 is involved in mediation of bradycardia and a decrease in cardiac contractility. Multiple alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]

Function:
The muscarinic acetylcholine receptor mediates various cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels through the action of G proteins. Primary transducing effect is adenylate cyclase inhibition.

Subunit:
Interacts with ARRB1 and ARRB2. Interacts with GNB2L1/RACK1; the interaction regulates CHRM2 internalization.

Subcellular Location:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein.

DISEASE:
Genetic variations in CHRM2 can influence susceptibility to major depressive disorder (MDD) [MIM:608516]. MDD is one of the most common psychiatric disorders. MDD is a complex trait characterized by one or more major depressive episodes without a history of manic, mixed, or hypomanic episodes. A major depressive episode is characterized by at least 2 weeks during which there is a new onset or clear worsening of either depressed mood or loss of interest or pleasure in nearly all activities. Four additional symptoms must also be present including changes in appetite, weight, sleep, and psychomotor activity; decreased energy; feelings of worthlessness or guilt; difficulty thinking, concentrating, or making decisions; or recurrent thoughts of death or suicidal ideation, plans, or attempts. The episode must be accompanied by distress or impairment in social, occupational, or other important areas of functioning.

Similarity:
Belongs to the G-protein coupled receptor 1 family. Muscarinic acetylcholine receptor subfamily. CHRM2 sub-subfamily.

Database links:

Entrez Gene: 1129 Human

Entrez Gene: 243764 Mouse

Entrez Gene: 397498 Pig

Entrez Gene: 81645 Rat

Omim: 118493 Human

SwissProt: P08172 Human

SwissProt: Q9ERZ4 Mouse

SwissProt: P06199 Pig

SwissProt: P10980 Rat

Unigene: 535891 Human

Unigene: 448632 Mouse

Unigene: 10752 Rat

Unigene: 200974 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产免国产免‘费 | 亚洲AV无码AV在线播放 | 天天躁人人躁人人躁狂躁 | 美日欧激情AV大片免费观看 | 亚洲AV永久精品爱情岛论坛 | 天天番号网 | 91啪在线 | 欧美一级淫片免费视频1 | 一二区免费视频 | 精品国产黄a∨片高清在线 欧美日韩精品综合 | 丝袜美腿亚洲一区二区 | 男人的天堂Aⅴ在线无码 | 国产免费一级 | 国产中文字字幕乱码无限 | 无码视频免费一区二区 | 亚洲精品乱码久久久久久久久久久久 | 亚洲精品国产精品国产 | 妖精视频一区二区 | 欧美a级毛片 | 韩国午夜理论a三级在线观看 | 三妻四妾免费 | 久久女同精品一区二区 | 国产99视频精品免费观看9 | 边啃奶头边躁狠狠躁玩爽在水里面 | 欧美丰满熟妇乱XXXXX图片 | 羞羞答答成人影院www | 啦啦啦资源在线观看视频 | www.夜夜草 | 啦啦啦www在线观看免费视频 | 亚洲av综合色区无码一区 | 国产毛片毛多水多的特级毛片 | av免费在线观看一区二区 | 少妇被大黑捧猛烈进出A片 久久亚洲视频网 | 国产一级视频在线 | 久久av麻豆 | 婷婷夜夜躁天天躁人人躁 | 韩国一大片a毛片 | 久久人人爽人人爽人人片 | 九色porny在线观看 | 新版中文在线官网 | 成人性生交A片免费看V |