超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
三级成网站,欧洲性XXXX免费视频在线观看,18禁强伦姧人妻又大又
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Phospho-cdc25C (Thr48)/FITC Conjugated antibody (bs-3482R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3482R-FITC
英文名稱 Rabbit Anti-Phospho-cdc25C (Thr48)/FITC Conjugated antibody
中文名稱 FITC標記的磷酸化細胞分裂周期蛋白25C抗體
別    名 cdc25C(Phospho-Thr48); cdc25C(Phospho Thr48); cdc25C(Phospho T48); CDC 25; Cdc 25C; CDC25; CDC25C; Cell division cycle 25 homolog C; Cell Division Cycle 25C; Cell Division Cycle 25C; Cell division cycle 25C protein; Dual specificity phosphatase Cdc25C; M phase inducer phosphatase 3; M-phase inducer phosphatase 3; Mitosis inducer CDC25; MPIP3; MPIP3_HUMAN; Phosphotyrosine phosphatase.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞周期蛋白  轉錄調節因子  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat,  (predicted: Human, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated Synthesised phosphopeptide derived from human cdc25C around the phosphorylation site of Thr48
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 and triggers entry into mitosis. It is also thought to suppress p53-induced growth arrest. Multiple alternatively spliced transcript variants of this gene have been described, however, the full-length nature of many of them is not known. [provided by RefSeq, Jul 2008]

Function:
Functions as a dosage-dependent inducer in mitotic control. Tyrosine protein phosphatase required for progression of the cell cycle. When phosphorylated, highly effective in activating G2 cells into prophase. Directly dephosphorylates CDK1 and activates its kinase activity.

Subunit:
Interacts with HIV-1 Vpr, thereby inactivating CDC25C phosphatase activity. Interacts with MAPK14 and 14-3-3 proteins.

Subcellular Location:
Nucleus.

Post-translational modifications:
Phosphorylated by CHEK1 and MAPK14 at Ser-216. This phosphorylation creates a binding site for 14-3-3 protein and inhibits the phosphatase. Phosphorylated by PLK4. Phosphorylated by PLK1, leading to activate the phosphatase activity. Phosphorylation by PLK3 at Ser-191 promotes nuclear translocation. Ser-198 is a minor phosphorylation site. Was initially reported to be phosphorylated by PLK3 at Ser-216 (PubMed:10557092). However, such phosphorylation by PLK3 was not confirmed by other groups. Phosphorylation at Thr-48, Thr-67, Ser-122, Thr-130, Ser-168 and Ser-214 occurs at G2 and G2-M transition and is probably catalyzed by CDK1. Ser-168 phosphorylation levels are lower than those at the other 5 CDK1 sites. Phosphorylation by CDK1 leads to increased activity.

Similarity:
Belongs to the MPI phosphatase family.
Contains 1 rhodanese domain.

Database links:

Entrez Gene: 995 Human

Omim: 157680 Human

SwissProt: P30307 Human

Unigene: 656 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

CDC25家族的組成哺乳動物中CDC25家族一共包括3種同源異構體(CDC25A、CDC25B、CDC25C),約有50%的序列同源,是一組在細胞周期調控中發揮巨大作用的蘇/酪氨酸雙功能酶 。不同的CDC25家族蛋白在細胞周期中的作用時相亦有差異,CDC25A和CDC25C分別在S期和M期發揮主要作用。
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 未发育成型小奶头毛片av | 日本道二区免费v | A片粗大的内捧猛烈进出视频 | 亚洲精品毛片av | 青青青青青国产费线在线观看 | 久久嫩草久久久精品三区 | 一久久久 | 欧美亚洲另类激情另类 | 中文字幕欧美日韩va免费视频 | 久久成人tv| 久久免费看少妇高潮a片特黄 | 三级国产网站 | 久久这里精品视频 | 青青青青久在线视频免费观看 | 91丨九色丨国产在线观看 | 毛片网站视频 | 国产路线1国产路线2022 | 含着她的花蒂啃到高潮在线观看 | 女邻居丰满的奶水 | 无码国产精品一区二区免费虚拟VR | 大地资源网免费观看高清 | 麻豆私人影院 | 无码中文日本精品一区 | 草逼网首页 | 日本又色又爽又黄的a片中文字幕 | 日韩a在线 | 欧美亚洲综合另类色妞网 | 99久久精品费精品 | 国色天香乱码区 | 国产精品久久久久久不久 | 国产精品毛片无遮挡 | 在线观看中文字幕一区二区 | 又粗又硬又黄又爽的免费视频 | 欧美日韩人妻精品一区二区在线 | 国模精品一区二区三区色天香 | 夏目友人帐第7季高清免费观看 | 亚洲成年人av | 国产成人综合精品无码 | 国产网红无码精品视频 | 久夜蜜汁av玖潮碰撩尤物 | 欧美亚洲91 |