超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲高清二区,91视频在线?看网站,夜夜摸日日操三级影院
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-HSD11B2/AP Conjugated antibody (bs-3618R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3618R-AP
英文名稱 Rabbit Anti-HSD11B2/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的羥基類固醇脫氫酶11β2抗體
別    名 Corticosteroid 11 beta dehydrogenase isozyme 2; 11 beta HSD2; 11 beta hydroxysteroid dehydrogenase type 2; 11 DH2; AME; AME1; HSD11K; HSD2; Hydroxysteroid 11 beta dehydrogenase 2; Hydroxysteroid 11 beta dehydrogenase isoenzyme 2; NAD dependent 11 beta hydroxysteroid dehydrogenase; SDR9C3; Short chain dehydrogenase/reductase family 9C, member 3.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  信號轉導  細胞凋亡  轉錄調節因子  激酶和磷酸酶  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse, Rat, Horse,  (predicted: Human, Dog, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 45kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human HSD11B2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
There are at least two isozymes of the corticosteroid 11-beta-dehydrogenase, a microsomal enzyme complex responsible for the interconversion of cortisol and cortisone. The type I isozyme has both 11-beta-dehydrogenase (cortisol to cortisone) and 11-oxoreductase (cortisone to cortisol) activities. The type II isozyme, encoded by this gene, has only 11-beta-dehydrogenase activity. In aldosterone-selective epithelial tissues such as the kidney, the type II isozyme catalyzes the glucocorticoid cortisol to the inactive metabolite cortisone, thus preventing illicit activation of the mineralocorticoid receptor. In tissues that do not express the mineralocorticoid receptor, such as the placenta and testis, it protects cells from the growth-inhibiting and/or pro-apoptotic effects of cortisol, particularly during embryonic development. Mutations in this gene cause the syndrome of apparent mineralocorticoid excess and hypertension. [provided by RefSeq, Feb 2010]

Function:
Catalyzes the conversion of cortisol to the inactive metabolite cortisone. Modulates intracellular glucocorticoid levels, thus protecting the nonselective mineralocorticoid receptor from occupation by glucocorticoids.

Subunit:
Interacts with ligand-free cytoplasmic NR3C2.

Subcellular Location:
Microsome. Endoplasmic reticulum.

Tissue Specificity:
Found in placenta, kidney, pancreas, prostate, ovary, small intestine and colon.

Similarity:
Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Database links:

Entrez Gene: 282434 Cow

Entrez Gene: 3291 Human

Entrez Gene: 15484 Mouse

Entrez Gene: 396948 Pig

Entrez Gene: 25117 Rat

Omim: 218030 Human

SwissProt: O77667 Cow

SwissProt: P80365 Human

SwissProt: P51661 Mouse

SwissProt: P51976 Rabbit

SwissProt: P50233 Rat

SwissProt: P50168 Sheep

Unigene: 1376 Human

Unigene: 5079 Mouse

Unigene: 10186 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

[DISEASE] Defects in HSD11B2 are the cause of apparent mineralocorticoid excess (AME) [MIM:218030]. An autosomal recessive form of low-renin hypertension. It is usually diagnosed within the first years of life and is characterized by polyuria and polydipsia, failure to thrive, hypernatremia, severe hypertension with low renin and aldosterone levels, profound hypokalemia with metabolic alkalosis, and most often nephrocalcinosis.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产在线播 | 日本黄色片在线 | 手机看片日韩在线 | 久久久久精彩视频 | 欧美日韩黄视频 | 国产精品色情一区二区三区 | 在线观看免费AV无码不卡 | 香蕉网在线 | 欧美写真一区 | 欧美一区二区二区 | 亚洲性毛片 | 亚洲成A人一区二区三区 | 亚洲热妇无码播放aV另类 | xxxx中国一级片 | 浮生影院大全免费观看 | 91精品视频免费看 | 国产精品视频99 | 人人草视频在线观看 | 日本不卡免费一区 | 日本一级淫片免费看 | 天天躁日日躁狠狠的躁天龙影院 | 国产精品国产三级国产aⅴ中文 | 久久嫩草精品久久久精品才艺表演 | 日本免费AⅤ欧美在线观看 亚洲av人人夜夜澡人人 | 国产精品自拍在线观看 | 女被男啪到哭的视频网站 | 国产一区毛片 | 亚洲AV无码精品色午夜果冻不卡 | 国产在线99 | 无码中出人妻中文字幕AV | 欧美精品综合A片在线观看 精品一区二区三区四 | 亚洲一区二区二区久久成人婷婷 | 亚洲国产AV一区二区三区四区 | 欧美性生交大片免费看A片免费 | 欧美高清一区 | 欧美三区二区一区 | 少妇被又粗又里进进出出 | 337P日本欧洲亚洲大胆 | 黄色网站小视频 | 中文字幕亚洲乱码 | 欧美啊啊啊视频 |