超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久夜色精品国产亚洲,草草视频免费,91精彩在线视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MT-ND1/Cy5.5 Conjugated antibody (bs-3685R-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3685R-Cy5.5
英文名稱 Rabbit Anti-MT-ND1/Cy5.5 Conjugated antibody
中文名稱 Cy5.5標記的NADH復合體1抗體
別    名 Mitochondrially encoded NADH dehydrogenase 1; MTND1; NAD1; NADH dehydrogenase subunit 1 (complex I); NADH1; ND1; NU1M_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  染色質和核信號  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MT-ND1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
MT-ND1 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]; also known as Leber optic atrophy. LHON is a maternally inherited disease resulting in acute bilateral blindness due to retinal degeneration predominantly in young men. Cardiac conduction defects and neurological defects have also been described, resulting in optic nerve degeneration and cardiac dysrhythmia. Defects in MT-ND1 may also be associated with mitochondrial susceptibility to Alzheimer disease (AD) and non insulin dependent diabetes mellitus (NIDDM).

Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein

DISEASE:
Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.
Defects in MT-ND1 are a cause of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000]. MELAS is a genetically heterogenious disorder, characterized by episodic vomiting, seizures, and recurrent cerebral insults resembling strokes and causing hemiparesis, hemianopsia, or cortical blindness.
Defects in MT-ND1 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT) [MIM:502500]. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques is the neurotoxic amyloid-beta-APP 40-42 peptide (s), derived proteolytically from the transmembrane precursor protein APP by sequential secretase processing. The cytotoxic C-terminal fragments (CTFs) and the caspase-cleaved products such as C31 derived from APP, are also implicated in neuronal death.
Note=Genetic variation in MT-ND1 might contribute ot the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM).

Similarity:
Belongs to the complex I subunit 1 family.

Database links:

Entrez Gene: 4535 Human

Entrez Gene: 17716 Mouse

Entrez Gene: 26193 Rat

SwissProt: P03886 Human

SwissProt: P03888 Mouse

SwissProt: P03889 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产自产在线视频一区 | 日韩AV一区三区 | 久草999| 7777精品伊久久久大香线蕉 | 张雨绮被揉到高潮下不了床 | 国产在线播放观看 | 日本一道本高清 | 国产露脸无码A区久久 | 久无码久无码AV无码 | 日本日本乱码伦视频免费 | 三男一女吃奶添下面 | 妖精视频一区二区 | 一色桃子视频 | 久久综合入口 | av观看成片免费网站 | 狠狠躁夜夜躁人人爽天天开心婷婷 | 日韩08精品 | 无码少妇一区二区浪潮免费 | 精品久久久久一区二区国产 | 嫩B人妻精品一区二区三区 avav国产 | 精品在线不卡 | 99国产精品视频免费观看一公开 | 国产AV无码专区亚洲AV桃花庵 | 免费看av在线网站网址 | 免费观看一级欧美片 | 我把护士日出水了视频 | 国内外成人在线视频 | 99香蕉国产精品偷在线观看 | A片粗大的内捧猛烈进出视频 | 日本XXXXZZX片免费观看 | 亚洲黄色免费av | 久久综合网址 | 丰满少妇三级全黄 | 国产精品白丝av在线观看播放 | 亚洲va在线视频 | 小妖精又紧又湿高潮H视频69 | 国产精品二十区 | 别揉我奶头~嗯~啊~免费网站 | 国产成人动漫 | 无码人妻丰满熟妇片毛片 | 成人做爰www |