超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
中文在线播放一区二区,久久国产亚洲AV无码,爱爱视频在线免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MT-ND1/PE Conjugated antibody (bs-3685R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3685R-PE
英文名稱 Rabbit Anti-MT-ND1/PE Conjugated antibody
中文名稱 PE標記的NADH復合體1抗體
別    名 Mitochondrially encoded NADH dehydrogenase 1; MTND1; NAD1; NADH dehydrogenase subunit 1 (complex I); NADH1; ND1; NU1M_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  染色質和核信號  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
細胞定位 細胞膜 線粒體
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MT-ND1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
MT-ND1 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]; also known as Leber optic atrophy. LHON is a maternally inherited disease resulting in acute bilateral blindness due to retinal degeneration predominantly in young men. Cardiac conduction defects and neurological defects have also been described, resulting in optic nerve degeneration and cardiac dysrhythmia. Defects in MT-ND1 may also be associated with mitochondrial susceptibility to Alzheimer disease (AD) and non insulin dependent diabetes mellitus (NIDDM).

Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein

DISEASE:
Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.
Defects in MT-ND1 are a cause of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000]. MELAS is a genetically heterogenious disorder, characterized by episodic vomiting, seizures, and recurrent cerebral insults resembling strokes and causing hemiparesis, hemianopsia, or cortical blindness.
Defects in MT-ND1 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT) [MIM:502500]. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques is the neurotoxic amyloid-beta-APP 40-42 peptide (s), derived proteolytically from the transmembrane precursor protein APP by sequential secretase processing. The cytotoxic C-terminal fragments (CTFs) and the caspase-cleaved products such as C31 derived from APP, are also implicated in neuronal death.
Note=Genetic variation in MT-ND1 might contribute ot the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM).

Similarity:
Belongs to the complex I subunit 1 family.

Database links:

Entrez Gene: 4535 Human

Entrez Gene: 17716 Mouse

Entrez Gene: 26193 Rat

SwissProt: P03886 Human

SwissProt: P03888 Mouse

SwissProt: P03889 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产成人精品亚洲日本在线桃色 | 精品人伦一区二区三区蜜桃免费 | 午夜在线视频免费 | 一级免费播放 | 久视频精品| 男人操女人视频免费观看 | 久久97超碰色中文字幕总站 | 久久久无码精品亚洲日韩蜜桃 | 亚洲国产中文字幕新在线vr | 不卡无在线一区二区三区观 | 影音先锋在线中文字幕 | 中文字幕av网站 | 欧美中文字幕一区 | 三及片日本 | 久久99精品国产99久久6男男 | 国产精品视频成人 | av鲁丝一区鲁丝二区鲁丝三区 | 绯色一区二区三区不卡少妇 | 激情视频网站 | HEYZO无码综合国产精蜜臀 | 亚洲国产成人久久久 | 久久亚洲经典 | 曰本不卡视频 | 精品久久久久久久久久国产潘金莲 | 日韩国产精品无码一区二区三区 | 欧美日韩一区二区三区精品 | 成年在线网站免费观看无广告 | 山东中年夫妇大白天露脸自拍 | 高清毛片在线观看 | 午夜免费1000 | 亚洲精品一区二区三区四区高清 | 亚洲精品视频在线免费播放 | 麻豆专媒体一区二区 | 91av网址 | 中文在线免费视频 | 七龙珠z国语在线观看 | CHINESE猛男浪小辉GAY国产 | 少妇扒开双腿让我看个够 | 久久国产免费 | 1000部啪啪未满十八勿入 | 97欧美一乱一性一交一视频 |