超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人三区,国产精品久久久久久久久久久久久久久久 ,曰韩内射六十七十老熟女影视
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MT-ND1/BF488 Conjugated antibody (bs-3685R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-3685R-BF488
英文名稱 Rabbit Anti-MT-ND1/BF488 Conjugated antibody
中文名稱 BF488標記的NADH復合體1抗體
別    名 Mitochondrially encoded NADH dehydrogenase 1; MTND1; NAD1; NADH dehydrogenase subunit 1 (complex I); NADH1; ND1; NU1M_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  染色質和核信號  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 36kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MT-ND1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
MT-ND1 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]; also known as Leber optic atrophy. LHON is a maternally inherited disease resulting in acute bilateral blindness due to retinal degeneration predominantly in young men. Cardiac conduction defects and neurological defects have also been described, resulting in optic nerve degeneration and cardiac dysrhythmia. Defects in MT-ND1 may also be associated with mitochondrial susceptibility to Alzheimer disease (AD) and non insulin dependent diabetes mellitus (NIDDM).

Function:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone

Subcellular Location:
Mitochondrion inner membrane; Multi-pass membrane protein

DISEASE:
Defects in MT-ND1 are a cause of Leber hereditary optic neuropathy (LHON) [MIM:535000]. LHON is a maternally inherited disease resulting in acute or subacute loss of central vision, due to optic nerve dysfunction. Cardiac conduction defects and neurological defects have also been described in some patients. LHON results from primary mitochondrial DNA mutations affecting the respiratory chain complexes.
Defects in MT-ND1 are a cause of mitochondrial encephalomyopathy with lactic acidosis and stroke-like episodes syndrome (MELAS) [MIM:540000]. MELAS is a genetically heterogenious disorder, characterized by episodic vomiting, seizures, and recurrent cerebral insults resembling strokes and causing hemiparesis, hemianopsia, or cortical blindness.
Defects in MT-ND1 may be associated with susceptibility to Alzheimer disease mitochondrial (AD-MT) [MIM:502500]. Alzheimer disease is a neurodegenerative disorder characterized by progressive dementia, loss of cognitive abilities, and deposition of fibrillar amyloid proteins as intraneuronal neurofibrillary tangles, extracellular amyloid plaques and vascular amyloid deposits. The major constituent of these plaques is the neurotoxic amyloid-beta-APP 40-42 peptide (s), derived proteolytically from the transmembrane precursor protein APP by sequential secretase processing. The cytotoxic C-terminal fragments (CTFs) and the caspase-cleaved products such as C31 derived from APP, are also implicated in neuronal death.
Note=Genetic variation in MT-ND1 might contribute ot the pathogenesis of non-insulin-dependent diabetes mellitus (NIDDM).

Similarity:
Belongs to the complex I subunit 1 family.

Database links:

Entrez Gene: 4535 Human

Entrez Gene: 17716 Mouse

Entrez Gene: 26193 Rat

SwissProt: P03886 Human

SwissProt: P03888 Mouse

SwissProt: P03889 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日本熟妇无码色视频在线观看 | 亚洲精品第一区二区三区 | 国产欧美久久久精品影院 | 久久国产精品高清一区二区三区 | 国产伦人人人人人人性 | 欧美大片久久国产欧美日韩精品 | 91麻豆精品国产91久久久久 | 国产真实乱免费高清视频 | 91新婚少妇在线播放 | 一本大道五月香蕉 | 免费色播 | 一区二区三区一级片 | 亚洲精品国产综合99久久夜夜嗨 | 久久色悠悠 | 亚洲午夜高清国产拍 | 丰满少妇被猛烈进入A片 | 亂倫近親相姦中文字幕视频 | 国产边打电话边被躁视频 | 巨乳一区| 成人美女黄网站色大免费的 | 97国产人妻人人爽人人澡 | 午夜免费视频福利 | 久久久久无码精品国产 | 91麻豆精品国产91久久久久 | 521av永久免费地址 | 一本色道久久综合精品竹菊 | 免费观看无遮挡WWW的视频 | 国产亚洲日本精品无码 | 被黑人各种姿势猛烈进出视频 | 亚洲自拍偷拍精品 | 男人扒开女人腿桶到爽免费 | 久久久久久国产精品美女 | 亚欧洲精品在线视频免费观看 | 黄色工厂这里只有精品 | 精品国产一区三区 | 成人午夜视频在线观看免费 | 天天躁夜夜躁狠狠躁婷婷 | 高清视频91| 啊灬啊灬轻点第一次和外国人 | 97精品国产97久久久久久粉红 | 韩国av永久免费 |