超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本一级淫片1000部,操人视频在线免费观看,bdsmvideos极端变态
Rabbit Anti-ATG4D/AP Conjugated antibody (bs-4009R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4009R-AP
英文名稱 Rabbit Anti-ATG4D/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的自噬相關(guān)蛋白4D抗體
別    名 9830134P12Rik; APG4 autophagy 4 homolog D; APG4 D; APG4, S. cerevisiae, homolog of, D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); Atg4d; ATG4D_HUMAN; Atg4dl; AUT like 4 cysteine endopeptidase; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagin-4; autophagy 4, S. cerevisiae, homolog of, D; autophagy related 4D, cysteine peptidase; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; Cysteine protease involved in autophagy; MGC31226.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  細(xì)胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATG4D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.

Subcellular Location:
Cysteine protease ATG4D: Cytoplasm.
Cysteine protease ATG4D, mitochondrial: Cytoplasm. Mitochondrion matrix. Note=Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.

Tissue Specificity:
Mainly expressed in skeletal muscle and, to a lower extent, in testis.

Post-translational modifications:
Cleaved by CASP3 during apoptosis which leads to increased activity. The cleavage by CASP3 reveals a cryptic mitochondrial targeting sequence immediately downstream of their canonical caspase cleavage sites which leads to mitochondroal import of the protein.

Similarity:
Belongs to the peptidase C54 family.

Database links:

Entrez Gene: 84971 Human

Entrez Gene: 235040 Mouse

Entrez Gene: 100141400 Pig

Entrez Gene: 686505 Rat

Omim: 611340 Human

SwissProt: Q86TL0 Human

SwissProt: Q8BGV9 Mouse

SwissProt: Q684M2 Pig

Unigene: 512799 Human

Unigene: 440165 Mouse

Unigene: 202643 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产成人啪精品视频免费软件 | 国产蜜臀 | 亚洲人成人一区二区三区 | 樱桃视频高清免费观看在线 | 三上悠亚久久精品 | 一区二区三区免费观看 | 91大神新作在线观看 | 日本黄色高清视频 | 亚洲一区二区三区无码久久 | 欧美午夜无码大片免费看 | 无码少妇一区二区三区免费 | www.嫩草影院 | 亚洲AⅤ久久一区二区三区 黄色一级大片 | 欧美a在线| 一区二区三区网 | 亚洲一区在线免费 | 少妇挑战三个黑人惨叫4p国语 | 精品一区二区三卡四卡网站 | a级片在线免费观看视频 | 超鹏97国语 | 欧美亚洲在线视频 | 日韩看片 | 亚洲成人手机在线观看 | 国内精品久久久久久99蜜桃 | 国产亚洲精品91 | 日韩乱码人妻无码系列中文字幕 | 久久精品日韩一区二区三区 | 亚洲国产精品欧美一二99 | 夜夜操人人 | 国产人无码a在线西瓜影音 A级毛片高清免费视频在线播放 | 免费观看国产美女裸体视频 | 高清videosgr欧美熟妇 | 在线日韩亚洲 | 久久久久久久久国产 | 国产在线无码视频一区二区三区 | 日韩高清片 | 欧美午夜精品久久久久久软件 | 日韩卡一卡二无线乱码新区仙踪林 | 另类成人专区 | 久久久久国产精品免费免费搜索 | 亚洲一二三四区不卡 |