超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
日本一级淫片1000部,操人视频在线免费观看,bdsmvideos极端变态
Rabbit Anti-ATG4D/AP Conjugated antibody (bs-4009R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號 bs-4009R-AP
英文名稱 Rabbit Anti-ATG4D/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標(biāo)記的自噬相關(guān)蛋白4D抗體
別    名 9830134P12Rik; APG4 autophagy 4 homolog D; APG4 D; APG4, S. cerevisiae, homolog of, D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); Atg4d; ATG4D_HUMAN; Atg4dl; AUT like 4 cysteine endopeptidase; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagin-4; autophagy 4, S. cerevisiae, homolog of, D; autophagy related 4D, cysteine peptidase; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; Cysteine protease involved in autophagy; MGC31226.  
規(guī)格價(jià)格 100ul/2980元 購買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 腫瘤  免疫學(xué)  細(xì)胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
產(chǎn)品應(yīng)用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATG4D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.

Subcellular Location:
Cysteine protease ATG4D: Cytoplasm.
Cysteine protease ATG4D, mitochondrial: Cytoplasm. Mitochondrion matrix. Note=Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.

Tissue Specificity:
Mainly expressed in skeletal muscle and, to a lower extent, in testis.

Post-translational modifications:
Cleaved by CASP3 during apoptosis which leads to increased activity. The cleavage by CASP3 reveals a cryptic mitochondrial targeting sequence immediately downstream of their canonical caspase cleavage sites which leads to mitochondroal import of the protein.

Similarity:
Belongs to the peptidase C54 family.

Database links:

Entrez Gene: 84971 Human

Entrez Gene: 235040 Mouse

Entrez Gene: 100141400 Pig

Entrez Gene: 686505 Rat

Omim: 611340 Human

SwissProt: Q86TL0 Human

SwissProt: Q8BGV9 Mouse

SwissProt: Q684M2 Pig

Unigene: 512799 Human

Unigene: 440165 Mouse

Unigene: 202643 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产SM调教视频在线观看 | 69vd视频| 女人性高朝床叫视频尖叫声 | 成人亚洲 | 亚洲国产婷婷影院 | 操操操日日日干干干 | 性视频网站入口 | 久久精品在线免费视频 | 久久在线免费观看视频 | 波多野结衣一区二区免费高清 | 成人无码AV一区二区三区 | 色综合久久久久久久久五月 | 91中文视频| 国产国拍精品亚洲 | 美女不带套日出白浆免费视频 | 成人av视频| 色综合久久中文娱乐网 | 亚洲国产精品日韩av不卡在线 | 暖暖免费高清日本社区在线观看 | 久久99精品久久久久久久青青日本 | 男人操女人网址 | 成人性生交免费大片2 | 欧美老人巨大xxxx做受 | 大地在线资源 | 国产精品久久久久久久久侵犯 | 久久精品国产一区 | java性无码hd中文 | 男同GAY毛片免费可播放 | 东北丰满熟女人妻与小伙 | 三妻四妾免费 | 国产尤物在线观看yw | 成年久久 | 99热网址| 2020日日夜夜噜噜噜com | 国产精品香蕉 | 欧美日在线观看 | 亚洲最大成人影院 | 国产美女在线精品 | www.youjizz.com最新 | 在线观看av永久免费 | 无码人妻aⅴ一区二区三区鲁大师 |