超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产亚洲在线观看,无码人妻一区二区三区AV,军人野外吮她的花蒂无码视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ATG4D/Cy5 Conjugated antibody (bs-4009R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4009R-Cy5
英文名稱 Rabbit Anti-ATG4D/Cy5 Conjugated antibody
中文名稱 Cy5標記的自噬相關蛋白4D抗體
別    名 9830134P12Rik; APG4 autophagy 4 homolog D; APG4 D; APG4, S. cerevisiae, homolog of, D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); Atg4d; ATG4D_HUMAN; Atg4dl; AUT like 4 cysteine endopeptidase; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagin-4; autophagy 4, S. cerevisiae, homolog of, D; autophagy related 4D, cysteine peptidase; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; Cysteine protease involved in autophagy; MGC31226.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  細胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATG4D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.

Subcellular Location:
Cysteine protease ATG4D: Cytoplasm.
Cysteine protease ATG4D, mitochondrial: Cytoplasm. Mitochondrion matrix. Note=Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.

Tissue Specificity:
Mainly expressed in skeletal muscle and, to a lower extent, in testis.

Post-translational modifications:
Cleaved by CASP3 during apoptosis which leads to increased activity. The cleavage by CASP3 reveals a cryptic mitochondrial targeting sequence immediately downstream of their canonical caspase cleavage sites which leads to mitochondroal import of the protein.

Similarity:
Belongs to the peptidase C54 family.

Database links:

Entrez Gene: 84971 Human

Entrez Gene: 235040 Mouse

Entrez Gene: 100141400 Pig

Entrez Gene: 686505 Rat

Omim: 611340 Human

SwissProt: Q86TL0 Human

SwissProt: Q8BGV9 Mouse

SwissProt: Q684M2 Pig

Unigene: 512799 Human

Unigene: 440165 Mouse

Unigene: 202643 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 综合激情久久综合激情 | 欧美久久综合网 | 影音先锋中文字幕亚洲资源站 | 国产精品久久久久久久久侵犯 | 国模两腿玉门打开图无码 | 中文字幕亚洲欧美另类 | 中文日韩欧美 | 亚洲av无一区二区三区 | 人人玩人人添人人澡免费 | 色综合久久网 | 亚洲AV无码一区东京热 | 亚洲乱码国产乱码精品精的特点 | 国产精品亚洲综合一区在线 | 任你操这里只有精品 | 欧美大片18禁AAA免费视频 | 日本边添边摸边做边爱边 | 天天摸天天透天天添 | 亚州久久 | 日韩v亚洲v欧美v精品综合 | 天堂蜜桃一区二区三区 | 精品久久久久久久毛片微露脸 | 色吧av色av | 精品白浆一区二区三区h | 亚洲狠狠做深爱婷婷影院 | 韩国三级黄色毛片 | 日本亚洲视频 | 在线中文字幕网 | 国产高清视频色欲 | 好吊妞视频这里只有精品 | 成人午夜在线视频 | 艳妇乳肉豪妇荡乳XXX | 狠狠躁夜夜躁人人爽超碰女h | 69精品久久久久9999不卡片 | 亚洲色无码A片一区二区情欲 | 一久久久 | 成人在线视 | 日韩有码在线观看 | 内射少妇36P亚洲区 日本免费一级片 | 日本美女一区二区三区插比 | gay18无套网站| 日韩一级片一区二区 |