超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲一区二区三区国产精华液 ,亚洲资源在线观看,国精产品在线wnw2544
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-ATG4D/BF647 Conjugated antibody (bs-4009R-BF647)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4009R-BF647
英文名稱 Rabbit Anti-ATG4D/BF647 Conjugated antibody
中文名稱 BF647標記的自噬相關蛋白4D抗體
別    名 9830134P12Rik; APG4 autophagy 4 homolog D; APG4 D; APG4, S. cerevisiae, homolog of, D; APG4D; ATG4 autophagy related 4 homolog D (S. cerevisiae); Atg4d; ATG4D_HUMAN; Atg4dl; AUT like 4 cysteine endopeptidase; AUT-like 4 cysteine endopeptidase; AUTL4; Autophagin 4; Autophagin-4; autophagy 4, S. cerevisiae, homolog of, D; autophagy related 4D, cysteine peptidase; Autophagy related cysteine endopeptidase 4; Autophagy related protein 4 homolog D; Autophagy-related cysteine endopeptidase 4; Autophagy-related protein 4 homolog D; Cysteine protease ATG4D; Cysteine protease involved in autophagy; MGC31226.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  免疫學  細胞凋亡  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 52kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ATG4D
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene belongs to the autophagy-related protein 4 (Atg4) family of C54 endopeptidases. Members of this family encode proteins that play a role in the biogenesis of autophagosomes, which sequester the cytosol and organelles for degradation by lysosomes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2013]

Function:
Cysteine protease ATG4D: Cysteine protease required for the cytoplasm to vacuole transport (Cvt) and autophagy. Cleaves the C-terminal amino acid of ATG8 family proteins MAP1LC3 and GABARAPL2, to reveal a C-terminal glycine. Exposure of the glycine at the C-terminus is essential for ATG8 proteins conjugation to phosphatidylethanolamine (PE) and insertion to membranes, which is necessary for autophagy. Has also an activity of delipidating enzyme for the PE-conjugated forms.
Cysteine protease ATG4D, mitochondrial: Plays a role as an autophagy regulator that links mitochondrial dysfunction with apoptosis. The mitochondrial import of ATG4D during cellular stress and differentiation may play important roles in the regulation of mitochondrial physiology, ROS, mitophagy and cell viability.

Subcellular Location:
Cysteine protease ATG4D: Cytoplasm.
Cysteine protease ATG4D, mitochondrial: Cytoplasm. Mitochondrion matrix. Note=Imported into mitochondrial matrix after cleavage by CASP3 during oxidative stress and cell death.

Tissue Specificity:
Mainly expressed in skeletal muscle and, to a lower extent, in testis.

Post-translational modifications:
Cleaved by CASP3 during apoptosis which leads to increased activity. The cleavage by CASP3 reveals a cryptic mitochondrial targeting sequence immediately downstream of their canonical caspase cleavage sites which leads to mitochondroal import of the protein.

Similarity:
Belongs to the peptidase C54 family.

Database links:

Entrez Gene: 84971 Human

Entrez Gene: 235040 Mouse

Entrez Gene: 100141400 Pig

Entrez Gene: 686505 Rat

Omim: 611340 Human

SwissProt: Q86TL0 Human

SwissProt: Q8BGV9 Mouse

SwissProt: Q684M2 Pig

Unigene: 512799 Human

Unigene: 440165 Mouse

Unigene: 202643 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天天躁日日躁狠狠躁日日躁 | 久久久人妻无码A片一区二区三区 | 国产无吗一区二区三区在线欢 | 一个人免费观看的WWW视频 | 亚洲日本欧美天堂在线手机版 | 国产一区二区精彩视频 | 137大胆人体在线观看 | 91色伦 | 大地资源在线观看免费中文版 | 中国黄色生活片 | 91夜色| 在线亚洲一区二区 | 懂色av噜噜一区二区三区av | 九九久久精品无码专区 | 91精品啪在线观看国产线免费 | 天天干在线视频论坛 | 91精品久久久久久粉嫩 | 综合网亚洲 | 极品久久久久久 | 国产精品亚洲综合一区二区三区 | 免费成人毛片 | 国产无遮挡又黄又爽网站 | 18禁美女裸体网站无遮挡 | 成年女人免费又黄又爽视频 | 成人午夜精品久久久久久久3d | 看曰本女人大战黑人视频 | 快看视频在线免费看 | 免费午夜影片 | 看全色黄大色大片女人爽吗 | 国产精品久久久久久久稀缺资源 | 久久精品九色 | 日韩一区二区久久久 | 天天干夜夜夜操 | 日本天天躁狠狠躁噜噜噜 | 国产一精品一aⅴ一免费 | 他掀开裙子舌头伸进去在线观看 | 日本成本人三级在线观看 | 人妻少妇不满足中文字幕 | 成人播放 | 久久久久久性高 | 欧美另类一区 |