超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲AV片无码久久五月,农村妇女精品一二区,九一视频在线免费观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Fas Ligand/FITC Conjugated antibody (bs-0216R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價

產品編號 bs-0216R-FITC
英文名稱 Rabbit Anti-Fas Ligand/FITC Conjugated antibody
中文名稱 FITC標記的FasL抗體
別    名 APO1L; Apoptosis (APO 1) antigen ligand 1; Fas-L; Apoptosis antigen ligand 1; APTL; CD178; CD-178; CD 178; CD95L; CD95 ligand; CD95-L; CD95L protein; FAS antigen ligand; Fas L; Fas Ligand; FASL; Fasl; Fas ligand (TNF superfamily member 6); Generalized lymphoproliferative disease; TNF superfamily member 6; TNFSF6; Tumor necrosis factor ligand superfamily member 6; TNFL6_HUMAN; Apoptosis antigen ligand; Tumor necrosis factor ligand superfamily member 6, membrane form; Tumor necrosis factor ligand superfamily member 6, soluble form; FASLG.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  免疫學  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Cow, )
產品應用 Flow-Cyt=2ug/Test ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 31kDa
細胞定位 細胞膜 
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Fas Ligand
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
FasL (CD95L) is a cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T cell mediated apoptosis and in T cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects. Homotrimer (Probable). May be released as type II membrane protein. Belongs to the tumor necrosis factor family

Function:
Cytokine that binds to TNFRSF6/FAS, a receptor that transduces the apoptotic signal into cells. May be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Binding to the decoy receptor TNFRSF6B/DcR3 modulates its effects.

Subunit:
Homotrimer (Probable). Interacts with ARHGAP9, BAIAP2L1, BTK, CACNB3, CACNB4, CRK, DLG2, DNMBP, DOCK4, EPS8L3, FGR, FYB, FYN, HCK, ITK, ITSN2, KALRN, LYN, MACC1, MIA, MPP4, MYO15A, NCF1, NCK1, NCK2, NCKIPSD, OSTF1, PIK3R1, PSTPIP1, RIMBP3C, SAMSN1, SH3GL3, SH3PXD2B, SH3PXD2A, SH3RF2, SKAP2, SNX33, SNX9, SORBS3, SPTA1, SRC, SRGAP1, SRGAP2, SRGAP3, TEC, TJP3 and YES1.

Subcellular Location:
Cell membrane; Single-pass type II membrane protein. Secreted. Cytoplasmic vesicle lumen. Lysosome lumen. Note=May be released into the extracellular fluid, probably by cleavage form the cell surface. Is internalized into multivesicular bodies of secretory lysosomes after phosphorylation by FGR and monoubiquitination.

Post-translational modifications:
N-glycosylated.
The soluble form derives from the membrane form by proteolytic processing.
Phosphorylated by FGR on tyrosine residues; this is required for ubiquitination and subsequent internalization.
Monoubiquitinated.

DISEASE:
Defects in FASLG are the cause of autoimmune lymphoproliferative syndrome type 1B (ALPS1B) [MIM:601859]; also known as Canale-Smith syndrome (CSS). ALPS is a childhood syndrome involving hemolytic anemia and thrombocytopenia with massive lymphadenopathy and splenomegaly.

Similarity:
Belongs to the tumor necrosis factor family.

Database links:

Entrez Gene: 356 Human

Entrez Gene: 14103 Mouse

Entrez Gene: 25385 Rat

Omim: 134638 Human

SwissProt: P48023 Human

SwissProt: P41047 Mouse

SwissProt: P36940 Rat

Unigene: 2007 Human

Unigene: 3355 Mouse

Unigene: 9725 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Fas-L 是一個與TNFRSF6/FAS 結合的細胞因子,一個轉導凋亡信號到細胞內的一個受體。他可能參與T-細胞調節凋亡細胞毒性和T-細胞的發育。調節凋亡的TNFRSF6/FAS 在外周組織耐受性方面和抗原刺激成熟淋巴細胞自殺中起作用。FasL誘導物受體TNFRSF6B/DcR3結合調節其作用。
FasL只表達于活化的淋巴細胞,但在小鼠睪丸中可見高表達的FasL;分子量為36-43kDa。屬于TNF家族。
產品圖片
Blank control:RAW264.7. Primary Antibody (green line): Rabbit Anti-Fas Ligand antibody (bs-0216R-FITC) Dilution: 2μg /10^6 cells; Isotype Control Antibody (orange line): Rabbit IgG . Protocol The cells were fixed with 4% PFA (10min at room temperature)and then permeabilized with 90% ice-cold methanol for 20 min at -20℃. The cells were then incubated in 5%BSA to block non-specific protein-protein interactions for 30 min at room temperature .Cells stained with Primary Antibody for 30 min at room temperature. Acquisition of 20,000 events was performed.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产网友愉拍精品视频手机人 | 2020年最新国产精品正在播放 | 国产精品av久久久久久久久久 | 中文在线a | 欧美熟妇的荡欲在线观看 | 国产精品美女久久久m | 亚洲一区综合 | 色就是色成人网 | 成人免费视频源码网站 | 伊人222成人综合网 午夜无人区免费网站 | 91精品毛片一区二区三区 | 丰满少妇xxxx| 久久久精品免费 | 国产无遮挡18禁无码网站免费 | 中文字幕人妻互换AV久久 | 精品人妻系列无码天堂 | 久久久久久久久久久久中文字幕 | 日韩高清中文字幕一区二区 | 99最新在线视频 | 亚洲日韩成人无码私人影院 | 91精品国产91久久久久久 | 人妻聚色窝窝人体WWW一区 | 国产草比视频 | 成人va在线 | 国产亚洲一区二区视频 | 久久久国产毛片 | 久久午夜精品影院一区 | 无码中文字幕日韩专区 | 99久久久久久中文字幕一区 | 骚妇BB双飞插 | 国产欧美综合在线观看第十页 | 水蜜桃视频免费在线观看 | 欧美综合影视自拍 | 2018国产精品视频麻 | 国产精品久久久久久久久免费相片 | 日韩av片在线播放 | 日日夜精品欧洲日日噜噜 | 亚洲一本之道高清乱码 | 中日韩欧美中文字幕 | 国产丝袜无码免费视频 | www.avtvtv.com新网址 |