超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
免费的成年私人影院网站,国产日韩专区,a级片免费在线
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-PDE5A/PE-Cy5 Conjugated antibody (bs-2349R-PE-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-2349R-PE-Cy5
英文名稱 Rabbit Anti-PDE5A/PE-Cy5 Conjugated antibody
中文名稱 PE-Cy5標記的磷酸二酯酶5A抗體
別    名 5''-cyclic phosphodiesterase; CGB PDE; CGB-PDE; CGBPDE; cGMP binding cGMP specific 3' 5' cyclic nucleotide phosphodiesterase; cGMP binding cGMP specific 35 cyclic nucleotide phosphodiesterase; cGMP binding cGMP specific phosphodiesterase; cGMP binding/cGMP specific phosphodiesterase; cGMP specific 3'5' cyclic phosphodiesterase; cGMP specific phosphodiesterase PDE5A2; cGMP specific phosphodiesterase type 5A; cGMP-binding cGMP-specific phosphodiesterase; cGMP-specific 3'; CN5A; CN5N; PDE 5; PDE 5A; PDE5; Pde5a; PDE5A_HUMAN; PDE5A1; Phosphodiesterase 5A; Phosphodiesterase 5A cGMP specific; Phosphodiesterase isozyme 5.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  細胞生物  免疫學  染色質和核信號  信號轉導  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產品應用 Flow-Cyt=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 100kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PDE5A
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The cGMP specific phosphodiesterase type 5A (PDE5A) family is comprised of 2 genes (PDE5A and PDE5B) each with multiple splice variants generated by RNA splicing and use of alternate initiation sites. The PDE5 is highly expressed in aorta and lungs, intestine, kidney adrenal gland cerebellum and cerebrum. In cerebellum the PDE5 is highly expressed during neonatal development in Purkinge cells layer. The PDE5 is also abundant in vascular smooth muscle regulating cGMP levels and vascular smooth muscle tonicity. In corpus cavernosum inhibition of PDE5 by sildenafil corrects erectile dysfunctions. The nitric oxide donor sodium notropurside (SNP) stimulate PDE5 activity by cGMP dependent kinase phosphorylation. PDE5A1 has 875 amino acids (99.5 kDa). The amino terminal 142 amino acid of the PDE5 gene showed no sequence homology with other PDEs and also contained serine 92 that is phosphorylated by cGMP kinases.

Function:
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

Tissue Specificity:
Expressed in aortic smooth muscle cells, heart, placenta, skeletal muscle and pancreas and, to a much lesser extent, in brain, liver and lung.

Post-translational modifications:
Phosphorylation is regulated by binding of cGMP to the two allosteric sites (By similarity). Phosphorylation by PRKG1 leads to its activation.

Similarity:
Belongs to the cyclic nucleotide phosphodiesterase family.
Contains 2 GAF domains.

Database links:
UniProtKB/Swiss-Prot: O76074.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 在线观看午夜看亚太视频 | 青青久草在线视频 | 四虎海外网址 | 国产亚洲美女精品久久久2020 | 人妻AV无码一区二区三区 | 1区2区视频 | 四虎永久在线精品免费一区二区 | 亚洲av永久无码精品国产精品 | 18禁真人抽搐一进一出免费 | 欧美日韩在线一区二区三区 | 久一在线视频 | 国产精品成人久久久 | 国产传煤欧美日韩成人动漫视频绯纹α | 48久久国产精品性色aⅴ人妻 | 啊灬啊灬啊灬快灬A片免费 亚洲不卡一区二区三区 | 波多野结衣AV一区二区无码 | 男生操女生视频免费看 | 国产麻豆高潮流白浆喷水免费网站 | 国产精品女人久久久 | 青青草免费在线观看视频 | 春色校园综合激情亚洲 | 日本不卡一区视频 | 中国产xxxxa片在线观看 | 国内精品a | 国产亚洲精品自在久久蜜TV | 亚洲三级性片 | 欧美一级视频播放 | 老司机免费视频一区二区三区 | 男女视频一区二区 | 麻豆传传媒久久久爱 | 欧美大片久久国产欧美日韩精品 | 成人做爽爽爽爽免费国产软件 | 制服丝袜国产在线无码 | a级片日本 | 一级无遮挡真人毛片黄色视频 | 真实国产精品视频400部 | 亞洲中文字幕第一 | 欧美视频二区欧美影视 | 黄色在线观看免费 | 日本无码一区二区三区在线观看 | 亚洲无人区在线观看AV |