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Rabbit Anti-OXCT1/BF488 Conjugated antibody (bs-5089R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5089R-BF488
英文名稱 Rabbit Anti-OXCT1/BF488 Conjugated antibody
中文名稱 BF488標記的含氧酸輔酶A轉移酶1抗體
別    名 mitochondrial; 3 oxoacid CoA transferase 1; 3-oxoacid-CoA transferase 1; OXCT; Oxct1; SCOT; Scot S; Scot-S; SCOT1_HUMAN; Somatic type succinyl CoA:3 oxoacid CoA transferase; Somatic-type succinyl-CoA:3-oxoacid-CoA-transferase; Succinyl CoA:3 ketoacid CoA transferase; Succinyl CoA:3 ketoacid coenzyme A transferase 1 mitochondrial; Succinyl CoA:3 oxoacid CoA transferase; Succinyl-CoA:3-ketoacid-coenzyme A transferase 1; EC 2.8.3.5 antibody.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  轉錄調節因子  線粒體  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 56kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human OXCT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Function:
Key enzyme for ketone body catabolism. Transfers the CoA moiety from succinate to acetoacetate. Formation of the enzyme-CoA intermediate proceeds via an unstable anhydride species formed between the carboxylate groups of the enzyme and substrate.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Abundant in heart, followed in order by kidney, brain, and muscle, whereas in liver it is undetectable; also detectable in leukocytes and fibroblasts.

DISEASE:
Defects in OXCT1 are a cause of SCOT deficiency (SCOTD) [MIM:245050].

Similarity:
Belongs to the 3-oxoacid CoA-transferase family.

Database links:

Entrez Gene: 5019 Human

Entrez Gene: 67041 Mouse

Entrez Gene: 690163 Rat

Omim: 601424 Human

SwissProt: P55809 Human

SwissProt: Q9D0K2 Mouse

SwissProt: B2GV06 Rat

Unigene: 278277 Human

Unigene: 13445 Mouse

Unigene: 98472 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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