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Rabbit Anti-GIP/RBITC Conjugated antibody (bs-0098R-RBITC)
訂購熱線:400-901-9800
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0098R-RBITC
英文名稱 Rabbit Anti-GIP/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的胃泌素抑制肽抗體
別    名 Gastric Inhibitory polypeptide; Gastric inhibitory polypeptide precursor; GIP; Glucose dependent insulinotropic polypeptide; Gastric Inhibitory Peptide; GIP_HUMAN; Glucose-dependent insulinotropic polypeptide; Incretin hormone.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 信號轉導  生長因子和激素  轉錄調節因子  糖尿病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 5/17kDakDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human GIP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
GIP (Gastric Inhibitory polypeptide ) belongs to the glucagon superfamily. The encoded protein is important in maintaining glucose homeostasis as it is a potent stimulator of insulin secretion from pancreatic beta-cells following food ingestion and nutrient absorption. This gene stimulates insulin secretion via its G protein-coupled receptor activation of adenylyl cyclase and other signal transduction pathways. It is a relatively poor inhibitor of gastric acid secretion. Mature GIP is a highly conserved 42 amino acid polypeptide belonging to the glucagon family. GIP is highly expressed as a pre-pro-protein in the duodenum and the jejunum. The mature secreted polypeptide acts as a potent stimulator of insulin secretion and a poor inhibitor of gastric acid secretion.

Function:
Potent stimulator of insulin secretion and relatively poor inhibitor of gastric acid secretion.

Subcellular Location:
Secreted.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 2695 Human

Omim: 137240 Human

SwissProt: P09681 Human

Unigene: 1454 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

胃泌素抑制肽(GIP)是胃腸道的一種由42個氨基酸組成的多肽激素,又稱為葡萄糖依賴性促胰島素多肽(glucose-dependent insulinotropic peptide,GIP)他強烈抑制胃分泌和運動,也可調節胰島素的釋放。GIP屬于Glucagon家族成員。
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