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Rabbit Anti-SIRT4/APC Conjugated antibody (bs-7537R-APC)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-7537R-APC
英文名稱 Rabbit Anti-SIRT4/APC Conjugated antibody
中文名稱 APC標記的沉默調節相關蛋白4抗體
別    名 NAD dependent deacetylase sirtuin 4; NAD-dependent ADP-ribosyltransferase sirtuin-4; Silent mating type information regulation 2 homolog; Sir 2 like 4; SIR 2 like protein 4; Sir2 like 4; SIR2 like protein 4; SIR2-like protein 4; SIR2L 4; SIR2L4; SIRT 4; Sirt4; SIRT4_HUMAN; Sirtuin (silent mating type information regulation 2 homolog) 4; Sirtuin (silent mating type information regulation 2 homolog) 4 (S. cerevisiae); Sirtuin 4; Sirtuin type 4; Sirtuin4.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 心血管  細胞生物  信號轉導  糖尿病  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, Pig, Cow, Horse, Rabbit, Sheep, Fruit Fly, Zebrafish)
產品應用
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 32kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SIRT4/SIR 2 like protein 4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity.

Function:
NAD-dependent protein ADP-ribosyl transferase. Catalyzes the transfer of ADP-ribosyl groups onto target proteins, including mitochondrial GLUD1. Inhibits GLUD1 enzyme activity. Down-regulates insulin secretion. Has no detectable protein deacetylase activity.

Subunit:
Interacts with GLUD1, IDE and SLC25A5.

Subcellular Location:
Mitochondrion matrix.

Tissue Specificity:
Detected in vascular smooth muscle and striated muscle. Detected in insulin-producing beta-cells in pancreas islets of Langerhans (at protein level). Widely expressed. Weakly expressed in leukocytes and fetal thymus.

Similarity:
Belongs to the sirtuin family. Class II subfamily.
Contains 1 deacetylase sirtuin-type domain.

Database links:

Entrez Gene: 519328 Cow

Entrez Gene: 23409 Human

Entrez Gene: 75387 Mouse

Entrez Gene: 100125349 Pig

Entrez Gene: 304539 Rat

Omim: 604482 Human

SwissProt: Q1JQC6 Cow

SwissProt: Q9Y6E7 Human

SwissProt: Q8R216 Mouse

Unigene: 50861 Human

Unigene: 332616 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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