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Rabbit Anti-LIF/PE-Cy5.5 Conjugated antibody (bs-1058R-PE-Cy5.5)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-1058R-PE-Cy5.5
英文名稱 Rabbit Anti-LIF/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標(biāo)記的白血病抑制因子抗體
別    名 DIA; CDF; Cholinergic Differentiation Factor; D factor; differentiation inhibitory activity; Differentiation stimulating factor; Differentiation-stimulating factor; Emfilermin; HILDA; Human interleukin in DA cells; Leukemia inhibitory factor; LIF; LIF_HUMAN; Melanoma derived LPL inhibitor; Melanoma-derived LPL inhibitor; MLPLI.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 腫瘤  細(xì)胞生物  免疫學(xué)  神經(jīng)生物學(xué)  生長因子和激素  細(xì)胞周期蛋白  細(xì)胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Rat,  (predicted: Human, Mouse, Dog, Pig, Cow, Rabbit, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human LIF
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
The leukemia inhibitory factor- LIF is a kind of cell factor that has various living creature functions.It has the leukemia cell of inducement to divide, regulating the growth metabolism of the bone organization, maintaining the basic characteristic of the Embryonicstem celles and promoting the mankind build the blood stem cell to divide to propagate, promote the cholinergic neuron to divide, obstruct the fat cell to synthesize, stimulate the muscle cell growth, regulate the liver cell to expect to respond the egg white to synthesize etc. in the acute the biology activity etc. function.

Function:
LIF has the capacity to induce terminal differentiation in leukemic cells. Its activities include the induction of hematopoietic differentiation in normal and myeloid leukemia cells, the induction of neuronal cell differentiation, and the stimulation of acute-phase protein synthesis in hepatocytes.

Subcellular Location:
Secreted.

Similarity:
Belongs to the LIF/OSM family.

Database links:

Entrez Gene: 3976 Human

Entrez Gene: 16878 Mouse

Omim: 159540 Human

SwissProt: P15018 Human

SwissProt: P09056 Mouse

Unigene: 2250 Human

Unigene: 4964 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

生長因子和激素( Growth Factor and Hormones)
白血病抑制因子-LIF是一種具有多種生物功能的細(xì)胞因子。它具有誘導(dǎo)白血病細(xì)胞分化,調(diào)節(jié)骨組織的生長代謝,維持胚胎干細(xì)胞(Embryonicstem celles細(xì)胞)的基本特征、促進(jìn)人類造血干細(xì)胞的分化增殖、促進(jìn)膽堿能神經(jīng)元的分化、阻礙脂肪細(xì)胞合成、刺激成肌細(xì)胞生長、調(diào)節(jié)肝細(xì)胞中急性期反應(yīng)蛋白的合成等生物學(xué)活性等作用.
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