超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久久精品国产99久久72部,天天狠天天插,色久综合一二码
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-SUPT16H/BF350 Conjugated antibody (bs-7879R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-7879R-BF350
英文名稱 Rabbit Anti-SUPT16H/BF350 Conjugated antibody
中文名稱 BF350標記的染色體特異性轉(zhuǎn)錄延伸因子抗體
別    名 CDC68; Chromatin specific transcription elongation factor 140 kDa subunit; Chromatin-specific transcription elongation factor 140 kDa subunit; Facilitates chromatin transcription complex subunit SPT16; FACT 140 kDa subunit; FACT; FACT complex subunit SPT16; FACTP140; FLJ10857; FLJ14010; hSPT16; SP16H_HUMAN; Suppressor of Ty 16 homolog; Supt16h.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  信號轉(zhuǎn)導(dǎo)  細胞周期蛋白  轉(zhuǎn)錄調(diào)節(jié)因子  細胞分化  表觀遺傳學(xué)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Dog, Pig, Cow, Horse, Rabbit, Zebrafish, )
產(chǎn)品應(yīng)用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 120kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human SUPT16H/CDC68
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment of the nucleosome following the passage of RNA polymerase II. The FACT complex is probably also involved in phosphorylation of 'Ser-392' of p53/TP53 via its association with CK2 (casein kinase II). Also involved in vitamin D-coupled transcription regulation via its association with the WINAC complex, a chromatin-remodeling complex recruited by vitamin D receptor (VDR), which is required for the ligand-bound VDR-mediated transrepression of the CYP27B1 gene.

Function:
Component of the FACT complex, a general chromatinfactor that acts to reorganize nucleosomes. The FACT complex isinvolved in multiple processes that require DNA as a template suchas mRNA elongation, DNA replication and DNA repair. Duringtranscription elongation the FACT complex acts as a histonechaperone that both destabilizes and restores nucleosomalstructure. It facilitates the passage of RNA polymerase II andtranscription by promoting the dissociation of one histone H2A-H2Bdimer from the nucleosome, then subsequently promotes thereestablishment of the nucleosome following the passage of RNApolymerase II. The FACT complex is probably also involved inphosphorylation of 'Ser-392' of p53/TP53 via its association withCK2 (casein kinase II). Also involved in vitamin D-coupledtranscription regulation via its association with the WINACcomplex, a chromatin-remodeling complex recruited by vitamin Dreceptor (VDR), which is required for the ligand-bound VDR-mediatedtransrepression of the CYP27B1 gene (By similarity).

Subunit:
Component of the FACT complex, a stable heterodimer ofSSRP1 and SUPT16H. Also component of a CK2-SPT16-SSRP1 complexwhich forms following UV irradiation, composed of SSRP1, SUPT16H,CSNK2A1, CSNK2A2 and CSNK2B. Component of the WINAC complex, atleast composed of SMARCA2, SMARCA4, SMARCB1, SMARCC1, SMARCC2,SMARCD1, SMARCE1, ACTL6A, BAZ1B/WSTF, ARID1A, SUPT16H, CHAF1A andTOP2B. Interacts with NEK9. Binds to histone H2A-H2B. Interactswith GTF2E2.

Subcellular Location:
Nucleus. Chromosome. Note=Colocalizes withRNA polymerase II on chromatin. Recruited to actively transcribedloci.

Tissue Specificity:
Ubiquitous.

Post-translational modifications:
ADP-ribosylated. ADP-ribosylation by PARP1 is induced bygenotoxic stress and correlates with dissociation of FACT fromchromatin.

Similarity:
Belongs to the peptidase M24 family. SPT16 subfamily.

Database links:

Entrez Gene: 514989 Cow

Entrez Gene: 612874 Dog

Entrez Gene: 11198 Human

Entrez Gene: 114741 Mouse

Entrez Gene: 305851 Rat

Omim: 605012 Human

SwissProt: E1BNP8 Cow

SwissProt: Q9Y5B9 Human

SwissProt: Q920B9 Mouse

Unigene: 213724 Human

Unigene: 21662 Mouse

Unigene: 93187 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 国产一区二区精品久久99 | 欧美性猛交性大交 | 人人人爽人人爽人人AV| 午夜久久国产 | 国产在线观看高清视频 | 国产精品18久久久不卡最新章节 | 九九九在线观看 | yp最新网站入口 | 欧美亚洲综合另类色妞网 | 日日骚一区二区三区 | 免费看欧美一级片 | 懂色av一区二区三区久久久 | 18毛片免费看 | 欧美激情在线观看一区二区三区 | 好好的日在线视频观看 | 亚洲成熟人网站 | 午夜欧美一区二区三区免费观看 | 4438激情网 | 欧美午夜精品久久久久久人妖 | 日韩美女乱婬免费看视频大黄 | 99国产视频| 亚洲一区二区三区无码久久 | 国产一国产二国产三国产四国产五 | 最新日韩欧美在线综合网 | 中文高清无码人妻 | 亚洲中文久久精品无码ww16 | 精品久久久一二三区 | 久久精品亚| 无遮挡边摸边吃奶边做视频 | 国产爆乳尤妮丝无码视频在线 | 黄色va视频 | 国产午夜精品一区 | 亚洲精品影视在线观看 | 国产永久av| VIDEOS日本熟妇人妻多毛 | 青青草视频在线观看视频 | 免费成人黄色 | 婷婷色播婷婷 | 中文字幕亚洲自拍 | 延禧攻略免费在线观看 | 国产精品一级特婬AV片在线看 |