超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
成人免费A级毛片无码片2023,青青草97国产精品麻豆,日日夜夜狠狠干
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-UBE2C/BF350 Conjugated antibody (bs-8357R-BF350)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8357R-BF350
英文名稱 Rabbit Anti-UBE2C/BF350 Conjugated antibody
中文名稱 BF350標記的泛素蛋白連接酶C抗體
別    名 Cyclin selective ubiquitin carrier protein; dJ447F3.2; Mitotic specific ubiquitin conjugating enzyme; UB E2C; UBCH 10; UBCH10; UBE 2C; Ube2c; UBE2C_HUMAN; Ubiquitin carrier protein C; Ubiquitin carrier protein E2 C; Ubiquitin carrier protein E2C; Ubiquitin conjugating enzyme E2 C; Ubiquitin conjugating enzyme E2C; Ubiquitin protein ligase C; Ubiquitin-conjugating enzyme E2 C; Ubiquitin-protein ligase C.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 20kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human UBE2C
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The ubiquitin (Ub) pathway involves three sequential enzymatic steps that facilitate the conjugation of Ub and Ub-like molecules to specific protein substrates. The first step requires the ATP-dependent activation of the Ub C-terminus and the assembly of multi-Ub chains by the Ub-activating enzyme known as the E1 component. The Ub chain is then conjugated to the Ub-conjugating enzyme (E2) to generate an intermediate Ub-E2 complex. The Ub-ligase (E3) then catalyzes the transfer of Ub from E2 to the appropriate protein substrate. UBE2C, also designated UBCH10 in human, is an E2 ubiquitin conjugating enzyme for the anaphase promoting complex (APC), which coordinates mitosis and G1 by sequentially promoting the degradation of key cell-cycle regulators. UBE2C is overexpressed in many different types of cancers and may be a potential therapeutic target.

Function:
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'- and 'Lys-48'-linked polyubiquitination. Acts as an essential factor of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated ubiquitin ligase that controls progression through mitosis. Acts by initiating 'Lys-11'-linked polyubiquitin chains on APC/C substrates, leading to the degradation of APC/C substrates by the proteasome and promoting mitotic exit.

Subunit:
Component of the APC/C complex.

Post-translational modifications:
Autoubiquitinated by the APC/C complex, leading to its degradation by the proteasome. Its degradation plays a central role in APC/C regulation, allowing cyclin-A accumulation before S phase entry. APC/C substrates inhibit the autoubiquitination of UBE2C/UBCH10 but not its E2 function, hence APC/C remaining active until its substrates have been destroyed.

Similarity:
Belongs to the ubiquitin-conjugating enzyme family.

Database links:
UniProtKB/Swiss-Prot: O00762.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 潘金莲一级淫片aaa 欧美综合二区 | 国产日韩综合性色av | 少妇嘿咻做爰吃奶摸视频网站 | 久久SE精品一区精品二区国产 | 欧美xx视频 | 久久久久亚洲最大xxxx | 天天操天天射综合网 | 日本xx高清 | 日本丰满大乳免费xxxx | 尤物久久av一区二区三区亚洲 | 婷婷久久丁香 | 欧美极品少妇xxxx | 亚洲毛片无码专区亚洲乱 | 欧洲一级黄 | 日本在线观看中文自拍 | 野狼第一精品社区 | 伊人aa| 我想看一级黄色毛片 | 又硬又水多又坚少妇18P | 久久99青青精品免费观看 | 日韩午夜在线观看 | 国产精品涩涩涩视频网站 | 尤物久久av一区二区三区亚洲 | 久久成人人人人精品欧 | 久久久久久国产一级毛片清晰版 | 亚洲黄色大片在线观看 | 日本理论片午午伦夜理片2021 | 99久久国语露脸精品国产 | 国产亚洲精品91 | 男人操女人网址 | 91无毛| 五月天我淫我色 | 色综合网在线 | 99久久国产综合精麻豆 | 天天爽夜夜爽视频 | 国产在线播放观看 | 自拍偷拍视频亚洲 | a级毛片毛片免费观看久潮 国产在线视频不卡一区二区三区 | 五月天人体艺术 | 成人免费视频一区二区 | 12孩岁女A处破娇小 成人久草 |