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Rabbit Anti-SLCO2A1/Biotin Conjugated antibody (bs-4710R-Bio)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4710R-Bio
英文名稱 Rabbit Anti-SLCO2A1/Biotin Conjugated antibody
中文名稱 生物素標記的溶質載體蛋白家族21成員2抗體
別    名 MATR1; Matrin F/G 1; OATP2A1; PGT; SO2A1_HUMAN; PHOAR2; Prostaglandin transporter; SLC21A2; Solute carrier family 21 (prostaglandin transporter) member 2; Solute carrier family 21 member 2; Solute carrier organic anion transporter family member 2A1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  信號轉導  通道蛋白  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Mouse,  (predicted: Human, Rat, )
產品應用 WB=1:50-200 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 70kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human PGT/Slco2a1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The organic anion transporting polypeptide (OATP) family of proteins play a role in drug absorption, distribution and excretion. OATP proteins mediate the uptake of a broad range of substrates, including bile salts, hormones, drugs and antibiotics, and they are expressed in various tissues, such as gut, brain, kidney and liver. PGT, also known as SLCO2A1 (solute carrier organic anion transporter family, member 2A1), SLC21A2 or OATP2A1, is a 643 amino acid multi-pass membrane protein that belongs to the organic anion transporter family. Expressed ubiquitously, PGT is thought to mediate the release, transepithelial transport and clearance of prostaglandins from cells to other areas of the body. The gene encoding PGT maps to human chromosome 3, which houses over 1,100 genes, including a chemokine receptor (CKR) gene cluster and a variety of human cancer-related gene loci.

Function:
May mediate the release of newly synthesized prostaglandins from cells, the transepithelial transport of prostaglandins, and the clearance of prostaglandins from the circulation. Transports PGD2, as well as PGE1, PGE2 and PGF2A.

Subcellular Location:
Cell membrane; Multi-pass membrane protein.

Tissue Specificity:
Ubiquitous.

Similarity:
Belongs to the organo anion transporter (TC 2.A.60) family. Contains 1 Kazal-like domain.

Database links:

Entrez Gene: 6578 Human

Omim: 601460 Human

SwissProt: Q92959 Human

Unigene: 518270 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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