超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩精品久久久久久久的张开腿让,18禁无遮挡无码网站免费,三级理论日韩欧美
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO11/FITC Conjugated antibody (bs-8472R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8472R-FITC
英文名稱 Rabbit Anti-FBXO11/FITC Conjugated antibody
中文名稱 FITC標記的F-box蛋白相關蛋白11抗體
別    名 F box protein 11; F-box only protein 11; FBX11; FBX11_HUMAN; Fbxo11; Fbxo 11; Fbxo-11; PRMT9; VIT-1; VIT1; Vitiligo associated protein VIT 1; Vitiligo-associated protein 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbxs class. It can function as an arginine methyltransferasethat symmetrically dimethylates arginine residues, and it acts asan adaptor protein to mediate the neddylation of p53, which leadsto the suppression of p53 function. This gene is known to bedown-regulated in melanocytes from patients with vitiligo, a skindisorder that results in depigmentation. Polymorphisms in this geneare associated with chronic otitis media with effusion andrecurrent otitis media (COME/ROM), a hearing loss disorder, and theknockout of the homologous mouse gene results in the deaf mousemutant Jeff (Jf), a single gene model of otitis media.Alternatively spliced transcript variants encoding distinctisoforms have been identified for this gene. [provided by RefSeq,Jun 2010].

Function:
Substrate recognition component of the a(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex whichmediates the ubiquitination and subsequent proteasomal degradationof target proteins. Probably recognizes and binds to phosphorylatedtarget proteins. Binds to and neddylates phosphorylated p53/TP53,inhibiting its transcriptional activity. SCF(FBXO11) does not seemto direct ubiquitination of TP53.

Subunit:
Component of the probable SCF(FBXWO11) complex consisting of CUL1, RBX1, SKP1 and FBXO11. Interacts with TP53.

Subcellular Location:
Nucleus

Tissue Specificity:
Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.

Similarity:
Contains 1 F-box domain.
Contains 19 PbH1 repeats.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 80204 Human

Entrez Gene: 225055 Mouse

Entrez Gene: 301674 Rat

Omim: 607871 Human

SwissProt: Q86XK2 Human

SwissProt: Q7TPD1 Mouse

SwissProt: Q7TSL3 Rat

Unigene: 352677 Human

Unigene: 386857 Mouse

Unigene: 36585 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 日韩手机在线 | 色偷偷人人澡人人爽人人模 | 久久久久国产精品熟女影院浪 | 91麻豆久久 | 欧美宗合 | 九色国产精品 | 久久久久国产综合精品 | 欧美日韩国产成人在线91 | 亚洲国产精品久久久久婷婷图片 | 永久免费av片在线观看全网站 | 日本丰满少妇裸体自慰 | 国产精品白丝AV嫩草影院 | 欧美日韩一本的免费高清视频 | 成人午夜精品视频 | 亚洲色最新高清AV网站 | 久久综合97丁香色香蕉 | 国产美女自慰在线观看 | 99久久夜色精品国产网站 | 亚洲在线中字幕 | 亚洲日韩成人无码私人影院 | 亚洲人xxxxxlmedjyf | 亚洲一区二区三区尿失禁 | 中文字幕永久 | 亚洲黄色小视频在线观看 | 久久久亚洲网站 | 国产精品亚洲一区二区三区正片 | 色呦呦欧美 | 日韩欧美中文字幕视频 | 在线免费一区二区 | 看曰本女人大战黑人视频 | 亚洲色欲久久久综合网 | 在线看片福利 | 种付おじさんと在线观看 | 色综合九九 | 国产放荡对白视频在线观看 | 国产特黄在线 | 欧美乱大交xxxxx春色视频 | 亚洲av无码不卡无码国产 | 国产人妻一区二区三区四区五区六 | 国产精品推荐制服丝袜 | 天堂在线国产 |