超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲妇女自偷自偷图片,精品国产精品国产自在久国产,综合久久综合
首頁 > 產(chǎn)品中心 > 標記一抗 > 產(chǎn)品信息
Rabbit Anti-FBXO11/BF555 Conjugated antibody (bs-8472R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-8472R-BF555
英文名稱 Rabbit Anti-FBXO11/BF555 Conjugated antibody
中文名稱 BF555標記的F-box蛋白相關(guān)蛋白11抗體
別    名 F box protein 11; F-box only protein 11; FBX11; FBX11_HUMAN; Fbxo11; Fbxo 11; Fbxo-11; PRMT9; VIT-1; VIT1; Vitiligo associated protein VIT 1; Vitiligo-associated protein 1.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細胞生物  免疫學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Pig, Cow, Horse, Sheep, )
產(chǎn)品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 104kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO11
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a member of the F-box protein familywhich is characterized by an approximately 40 amino acid motif, theF-box. The F-box proteins constitute one of the four subunits ofubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box),which function in phosphorylation-dependent ubiquitination. TheF-box proteins are divided into 3 classes: Fbws containing WD-40domains, Fbls containing leucine-rich repeats, and Fbxs containingeither different protein-protein interaction modules or norecognizable motifs. The protein encoded by this gene belongs tothe Fbxs class. It can function as an arginine methyltransferasethat symmetrically dimethylates arginine residues, and it acts asan adaptor protein to mediate the neddylation of p53, which leadsto the suppression of p53 function. This gene is known to bedown-regulated in melanocytes from patients with vitiligo, a skindisorder that results in depigmentation. Polymorphisms in this geneare associated with chronic otitis media with effusion andrecurrent otitis media (COME/ROM), a hearing loss disorder, and theknockout of the homologous mouse gene results in the deaf mousemutant Jeff (Jf), a single gene model of otitis media.Alternatively spliced transcript variants encoding distinctisoforms have been identified for this gene. [provided by RefSeq,Jun 2010].

Function:
Substrate recognition component of the a(SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex whichmediates the ubiquitination and subsequent proteasomal degradationof target proteins. Probably recognizes and binds to phosphorylatedtarget proteins. Binds to and neddylates phosphorylated p53/TP53,inhibiting its transcriptional activity. SCF(FBXO11) does not seemto direct ubiquitination of TP53.

Subunit:
Component of the probable SCF(FBXWO11) complex consisting of CUL1, RBX1, SKP1 and FBXO11. Interacts with TP53.

Subcellular Location:
Nucleus

Tissue Specificity:
Isoform 5 is expressed in keratinocytes, fibroblasts and melanocytes.

Similarity:
Contains 1 F-box domain.
Contains 19 PbH1 repeats.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 80204 Human

Entrez Gene: 225055 Mouse

Entrez Gene: 301674 Rat

Omim: 607871 Human

SwissProt: Q86XK2 Human

SwissProt: Q7TPD1 Mouse

SwissProt: Q7TSL3 Rat

Unigene: 352677 Human

Unigene: 386857 Mouse

Unigene: 36585 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 麻豆传媒影视 | 自拍偷自拍亚洲精品情侣 | 一区二区三区在线视频播放 | 欧美区一区二 | 91麻豆精品国产91久久久无需广告 | 少妇性色午夜淫片aaa播放5 | 成人影院在线观看 | 欧美一级淫片aaaaaaa视频 | 欧美一二三区在线观看 | 亚洲精品一区二区三区精品 | 少妇愉情理伦片丰满丰满 | 日韩美女乱婬免费看视频大黄 | 中文字幕第一页卡通动漫在线 | 777亚洲熟妇自拍无码区 | 久久精品三 | 调教女m屁股撅虐调教 | 少妇人妻偷人精品视蜜桃 | 玖玖玖在线观看 | 久久久久久女乱国产 | 卡一卡2卡3卡4精品乱码免费 | 扒开女人内裤猛进猛出免费视频 | 欧美三级不卡在线播放 | 亚洲精品欧美视频 | 91新婚少妇在线播放 | 日本a级片免费 | 国产高清在线免费视频 | 国精产品99永久一区一区 | 人与禽交av在线播放 | 无码一卡二卡三卡四卡 | 午夜精品久久久久久久男人的天堂 | 人人dvd | 国产成人AV综合久久视色 | 久久久久久久久久久国产 | 波多野结衣乳巨码无在线播放 | 国产第五页 | 久久精品国产av一区二区蜜臀 | 一二三四日本高清社区5 | 国精产品深夜免费麦片 | 超碰人人人 | 中文字幕色一区二区 | 久久久精品国产一区二区 |