超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲色最新高清AV网站,999亚洲欲妇,亚洲日韩∨A无码中文字幕
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO7/Gold Conjugated antibody (bs-8489R-Gold)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-8489R-Gold
英文名稱 Rabbit Anti-FBXO7/Gold Conjugated antibody
中文名稱 膠體金標記的F-box蛋白家族FBXO7抗體
別    名 F box only protein 7; F box protein 7; F-box protein 7; FBX; FBX07; FBX7; PARK15; PKPS;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  細胞周期蛋白  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO7) formed of CUL1, SKP1, RBX1 and FBXO7. Interacts via its C-terminal proline-rich region with DLGAP5. Interacts with BIRC2. Interacts with CDK6 and promotes its interaction with D-type cyclin.

Subcellular Location:
Cytoplasm. Nucleus

DISEASE:
Defects in FBXO7 are the cause of Parkinson disease type 15 (PARK15) [MIM:260300]; also known as parkinsonian-pyramidal syndrome. A neurodegenerative disorder characterized by parkinsonian and pyramidal signs. Clinical manifestations include tremor, bradykinesia, rigidity, postural instability, spasticity, mainly in the lower limbs, and hyperreflexia.

Similarity:
Contains 1 F-box domain.

Database links:
UniProtKB/Swiss-Prot: Q9Y3I1.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美一级性生活 | 亚欧成A人无码精品VA片 | 亚洲一卡二卡三卡四卡无卡网站 | 亚洲熟啪啪偷拍 | 女人被狂躁高潮啊的视频在线看 | 国产特级毛片AAAAAA高潮流水 | 欧美国产伦久久久久久久 | 亚洲精品无码一区二区三区在线高 | 亚洲成人精品久久 | 在线观看一区二区三区国产免费 | 啊灬啊灬轻点第一次和外国人 | 久久久久亚洲最大xxxx | 国产人人爱 | 日本熟妇牲交视频 | 亚洲AV成人午夜福利在线观看 | 亚洲中文久久久久久精品 | 护士hd白色free性xxxⅹ | 亚洲国产精品一区二区三区四区 | 亚洲性xxxx| 观看av在线| 日本BBW丰满牲交片 a级片免费播放 | 女同免费毛片在线播放 | 蜜桃国精产品二三三区视频 | 911精品影院在线观看 | 中文字幕有码无码人妻在线 | 久久无码色综合中文字幕 | 色综合天天综合高清 | 亚洲国内自拍愉拍 | 国产成年人免费视频 | 福利午夜国产网站在线不卡 | 国产边打电话边被躁视频 | 91精品啪在线观看国产线免费 | 蜜桃视频精品区 | 亚洲国产第一区 | 久中文字幕 | 精品小视频在线 | 亚洲视频在线观看一级片 | gay男男自慰免费播放 | 精品亚洲aⅴ一区二区三区 深夜激情视频 | 欧美性xxxx禁忌 | 中文无码天天AV天天爽 |