超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
欧美日产欧美日产国产精品,手机中文字幕永久在线,欧美日韩网站
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FBXO7/AP Conjugated antibody (bs-8489R-AP)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-8489R-AP
英文名稱 Rabbit Anti-FBXO7/AP Conjugated antibody
中文名稱 堿性磷酸酶(AP)標記的F-box蛋白家族FBXO7抗體
別    名 F box only protein 7; F box protein 7; F-box protein 7; FBX; FBX07; FBX7; PARK15; PKPS;   
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  細胞周期蛋白  表觀遺傳學  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Cow, Horse, Sheep, )
產品應用 IHC-P=1:50-200 IHC-F=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 59kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FBXO7
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
FBXO7, also known as FBX, FBX7 or PKPS, is a 522 amino acid protein that contains one F-box domain and functions as a component of the SCF complex. Defects in the gene encoding FBXO7 are associated with parkinsonian-pyramidal syndrome (PKPS), a hypokinetic rigid disorder that exhibits Parkinsonian and pyramidal-associated symptoms.The FBXO7 gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class and it may play a role in regulation of hematopoiesis. Alternatively spliced transcript variants of this gene have been identified with the full-length natures of only some variants being determined.

Function:
Substrate recognition component of a (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Recognizes BIRC2 and DLGAP5.

Subunit:
Part of the SCF (SKP1-CUL1-F-box) E3 ubiquitin-protein ligase complex SCF(FBXO7) formed of CUL1, SKP1, RBX1 and FBXO7. Interacts via its C-terminal proline-rich region with DLGAP5. Interacts with BIRC2. Interacts with CDK6 and promotes its interaction with D-type cyclin.

Subcellular Location:
Cytoplasm. Nucleus

DISEASE:
Defects in FBXO7 are the cause of Parkinson disease type 15 (PARK15) [MIM:260300]; also known as parkinsonian-pyramidal syndrome. A neurodegenerative disorder characterized by parkinsonian and pyramidal signs. Clinical manifestations include tremor, bradykinesia, rigidity, postural instability, spasticity, mainly in the lower limbs, and hyperreflexia.

Similarity:
Contains 1 F-box domain.

Database links:
UniProtKB/Swiss-Prot: Q9Y3I1.1

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲真人无码永久在线 | 午夜激情毛片 | 好骚综合av | 国模两腿玉门打开图无码 | 毛片TV网站无套内射TV网站 | 日本免费高清一区二区 | 激情综合网天天干 | 国产午夜精品视频免费不卡 | 久久久久久久极品内射 | 天堂中文av | 欧亚精品卡一卡二卡三 | 直接看不卡的日本无码视频 | 无码AV无码一区二区 | 97精品国产97久久久久久粉红 | 色综合九九 | 老师掀起裙子让我把j放进去视频 | 国产妇女馒头高清泬20P多 | 女人夜夜春高潮爽A∨片传媒 | 99久久亚洲精品蜜臀 | 好好的日在线视频观看 | 久久久久久逼 | 欧美性高潮 | 精品亚洲永久 | 48沈阳熟女高潮嗷嗷叫 | 亚洲欧美成人一区二区 | 日本不卡免费播放 | 日韩精品一区在线播放 | 国产高清视频色欲 | 免费成人毛片 | 九九热在线免费观看 | 成人午夜精品久久久久久久3d | 国产网友愉拍精品视频手机人 | 欧美激情精品 | 狠狠爱网址 | 国产一区二区网 | 久久成人精品视频 | 国产成人啪精品视频免费视频 | 国产欧美日韩精品第一区二区三区 | 最新在线中文字幕 | 您好星期六2024最新免费观看 | 米奇午夜 |