超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
麻豆爱爱,三年片在线观看大全中国,日本久久爱
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-APAF1(NT)/BF555 Conjugated antibody (bs-0059R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-0059R-BF555
英文名稱 Rabbit Anti-APAF1(NT)/BF555 Conjugated antibody
中文名稱 BF555標記的凋亡蛋白活性因子-1抗體(N端)
別    名 APAF 1; APAF1; APAF-1; Apoptotic peptidase activating factor 1; Apoptotic protease activating factor; CED 4; CED4; KIAA0413; APAF_HUMAN; Apoptotic protease-activating factor 1.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  信號轉導  細胞凋亡  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Rat,  (predicted: Human, Mouse, Chicken, Dog, Cow, Horse, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 137kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Apaf-1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene encodes a cytoplasmic protein that initiates apoptosis. This protein contains several copies of the WD-40 domain, a caspase recruitment domain (CARD), and an ATPase domain(NB-ARC). Upon binding cytochrome c and dATP, this protein forms an oligomeric apoptosome. The apoptosome binds and cleaves caspase 9 preproprotein, releasing its mature, activated form. Activated caspase 9 stimulates the subsequent caspase cascade that commits the cell to apoptosis. Alternative splicing results in several transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008].

Function:
Oligomeric Apaf-1 mediates the cytochrome c-dependent autocatalytic activation of pro-caspase-9 (Apaf-3), leading to the activation of caspase-3 and apoptosis. This activation requires ATP. Isoform 6 is less effective in inducing apoptosis.

Subunit:
Monomer. Oligomerizes upon binding of cytochrome c and dATP. Oligomeric Apaf-1 and pro-caspase-9 bind to each other via their respective NH2-terminal CARD domains and consecutively mature caspase-9 is released from the complex. Pro-caspase-3 is recruited into the Apaf-1-pro-caspase-9 complex via interaction with pro-caspase-9. Interacts with APIP. Interacts (via CARD and NACHT domains) with NAIP/BIRC1 (via NACHT domain).

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Ubiquitous. Highest levels of expression in adult spleen and peripheral blood leukocytes, and in fetal brain, kidney and lung. Isoform 1 is expressed in heart, kidney and liver.

Similarity:
Contains 1 CARD domain.
Contains 1 NB-ARC domain.
Contains 13 WD repeats.

Database links:

Entrez Gene: 317 Human

Entrez Gene: 11783 Mouse

Entrez Gene: 78963 Rat

Omim: 602233 Human

SwissProt: O14727 Human

SwissProt: O88879 Mouse

SwissProt: Q9EPV5 Rat

Unigene: 728891 Human

Unigene: 220289 Mouse

Unigene: 64522 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

Apaf-1 (Apoptosis protease activating factor-1)調節細胞色素C依賴的Caspase-9原的自動催化活性,導致Caspase-3 的激活和引起凋亡。
Apaf-1在成年人的脾臟、外周血白細胞、腎臟、肺和胎兒腦、腎、肺中高水平表達。
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 欧美精品久久久久久久久老牛影院 | 国产精品一区二区精品视频免费看 | 99久久国产综合精品1 | 五月婷婷中文字幕 | 美女亚洲一区 | 国产香港明星裸体XXXX视频 | 久久亚洲色WWW成人图片 | 高清中文字幕一区二区三区 | 国产路线1国产路线2022 | AV无码久久久久不卡网站蜜桃 | 激情丁香| 韩国三级按摩 | 久久草草影视免费网 | 日本三级免费片 | 人人澡人人干 | 国产成人无码精品久免费 | 成人区一区二区三区 | 人人妻人人玩人人澡人人爽 | 在线看片免费人成视频无毒 | aykkk伦理| 精品国产乱码久久久久久影片 | 在线观看免费AV无码不卡 | 麻豆综合在线 | 国产亚洲天堂网 | 亚洲精品无码AV专区最新 | 国产高清一区二区三区四区 | 少妇午夜| av解说在线精品 | 最新日韩欧美在线综合网 | 日韩操操操| 欧美丰满熟妇xxxx性 | 日韩乱码人妻无码系列中文字幕 | www.青青草.com| 久久精品国产av一区二区三区 | 色婷婷综合激情综在线播放 | 国产综合网站 | 久久国产精99精产国高潮 | www.av在线 | 亚洲人成网站999久久久综合 | 欧美亚洲综合另类色妞网 | 国产69视频在线观看 |