超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
中文字幕一区久久,美女视频一级片,国产精品九九九九九九九
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GRPP/Cy3 Conjugated antibody (bs-4585R-Cy3)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-4585R-Cy3
英文名稱 Rabbit Anti-GRPP/Cy3 Conjugated antibody
中文名稱 Cy3標記的腸高血糖素相關肽抗體
別    名 glicentin-related polypeptide; GCG; Glicentin related polypeptide; Glucagon precursor; GRPP; Oxyntomodulin; OXM; OXY; GLUC_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  心血管  免疫學  神經生物學  信號轉導  通道蛋白  糖尿病  內分泌病  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 3.3kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Rat GRPP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon. [provided by RefSeq].

Function:
Glucagon plays a key role in glucose metabolism and homeostasis. Regulates blood glucose by increasing gluconeogenesis and decreasing glycolysis. A counterregulatory hormone of insulin, raises plasma glucose levels in response to insulin-induced hypoglycemia. Plays an important role in initiating and maintaining hyperglycemic conditions in diabetes.
GLP-1 is a potent stimulator of glucose-dependent insulin release. Play important roles on gastric motility and the suppression of plasma glucagon levels. May be involved in the suppression of satiety and stimulation of glucose disposal in peripheral tissues, independent of the actions of insulin. Have growth-promoting activities on intestinal epithelium. May also regulate the hypothalamic pituitary axis (HPA) via effects on LH, TSH, CRH, oxytocin, and vasopressin secretion. Increases islet mass through stimulation of islet neogenesis and pancreatic beta cell proliferation. Inhibits beta cell apoptosis.
GLP-2 stimulates intestinal growth and up-regulates villus height in the small intestine, concomitant with increased crypt cell proliferation and decreased enterocyte apoptosis. The gastrointestinal tract, from the stomach to the colon is the principal target for GLP-2 action. Plays a key role in nutrient homeostasis, enhancing nutrient assimilation through enhanced gastrointestinal function, as well as increasing nutrient disposal. Stimulates intestinal glucose transport and decreases mucosal permeability.
Oxyntomodulin significantly reduces food intake. Inhibits gastric emptying in humans. Suppression of gastric emptying may lead to increased gastric distension, which may contribute to satiety by causing a sensation of fullness.
Glicentin may modulate gastric acid secretion and the gastro-pyloro-duodenal activity. May play an important role in intestinal mucosal growth in the early period of life.

Subcellular Location:
Secreted.

Tissue Specificity:
Glucagon is secreted in the A cells of the islets of Langerhans. GLP-1, GLP-2, oxyntomodulin and glicentin are secreted from enteroendocrine cells throughout the gastrointestinal tract. GLP1 and GLP2 are also secreted in selected neurons in the brain.

Post-translational modifications:
Proglucagon is post-translationally processed in a tissue-specific manner in pancreatic A cells and intestinal L cells. In pancreatic A cells, the major bioactive hormone is glucagon cleaved by PCSK2/PC2. In the intestinal L cells PCSK1/PC1 liberates GLP-1, GLP-2, glicentin and oxyntomodulin. GLP-1 is further N-terminally truncated by post-translational processing in the intestinal L cells resulting in GLP-1(7-37) GLP-1-(7-36)amide. The C-terminal amidation is neither important for the metabolism of GLP-1 nor for its effects on the endocrine pancreas.

Similarity:
Belongs to the glucagon family.

Database links:

Entrez Gene: 2641 Human

Entrez Gene: 14526 Mouse

Entrez Gene: 24952 Rat

Omim: 138030 Human

SwissProt: P01272 Cow

SwissProt: P01275 Human

SwissProt: P01274 Pig

SwissProt: P06883 Rat

Unigene: 516494 Human

Unigene: 54383 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 精品免费看国产一区二区 | 欧美亚洲91 | 国产三级精品三级男人的天堂 | 久久久精品理论A级A片 | 国产成人综合精品无码 | 人摸人人人澡人人超碰 | 亚洲AV成人综合网久久 | 在线免费黄色片 | 国产精品国产三级国产aⅴ原创 | 国产网红无码精品视频 | 欧美丰满熟妇VAIDEOS | av在线网站免费观看 | 男人狂桶女人出白浆免费视频 | 91桃色视频在线观看 | 天堂AV日韩AV无码AV | 人妻无码AV中文系列久久兔费 | 国产精品扒开腿做爽爽的视频 | 亚洲一区日本 | 欧美13一14娇小性 | 午夜影视免费 | 国产午夜精品视频免费不卡 | 久久久www成人免费无遮挡大片 | 欧美特黄视频在线观看 | 亚洲av成人片在线观看 | 人体内射精一区二区三区 | 免费1级a做爰片在线观看 | 78影视传媒有限公司 | 五十路熟女の豊満な肉体 | 麻豆影院在线播放 | 91麻豆国产福利在线观看宅福利 | 国产精品亚洲А∨天堂网 | 久久影院午夜 | 久久久久亚洲精品天堂 | 国产一区视频在线免费观看 | 亚洲精品一线二线在线播放 | 少妇愉情理伦片丰满丰满 | 久久69精品久久久久久国产越南 | 超碰aⅴ人人做人人爽 | 久久国产自偷自偷免费一区调 | 亚洲一区在线免费 | 亚洲国产国产亚洲一二三 |