超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产voyeur精品偷窥222,成人黄色a视频,无码高潮喷水在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-MBD1/PE-Cy5.5 Conjugated antibody (bs-5915R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-5915R-PE-Cy5.5
英文名稱 Rabbit Anti-MBD1/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的甲基化CpG結合蛋白抗體
別    名 CXXC 3; CXXC3; MBD 1; MBD1; MECP1 COMPLEX; Methyl CpG binding domain protein 1; Methyl CpG binding domain protein 1 isoform PCM1; Methyl CpG binding protein MBD1; Methyl CpG binding protein splice variant 1; Methyl CpG binding protein splice variant 2; Methyl CpG binding protein splice variant 3; Methyl CpG binding protein splice variant 4; PCM 1; PCM1; Protein containing methyl CpG binding domain 1; Regulator of fibroblast growth factor 2 (FGF 2) transcription; RFT; The regulator of fibroblast growth factor 2(FGF 2) transcription; MBD1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  免疫學  染色質和核信號  細胞周期蛋白  細胞分化  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, )
產品應用 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 60kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human MBD1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
DNA methylation, or the addition of methyl groups to cytosine bases in the dinucleotide CpG, is imperative to proper development and regulates gene expression. The methylation pattern involves the enzymatic processes of methylation and demethylation. The demethylation enzyme was recently found to be a mammalian protein, which exhibits demethylase activity associated to a methyl-CpG-binding domain (MBD). The enzyme is able to revert methylated cytosine bases to cytosines within the particular dinucleotide sequence mdCpdG by catalyzing the cleaving of the methyl group as methanol. MeCP2 and MBD1 (PCM1) are first found to repress transcription by binding specifically to methylated DNA. MBD2 and MBD4 (also known as MED1) were later found to colocalize with foci of heavily methylated satellite DNA and believed to mediate the biological functions of the methylation signal. Surprisingly, MBD3 does not bind methylated DNA both in vivo and in vitro. MBD1, MBD2, MBD3, and MBD4 are found to be expressed in somatic tissues, but the expression of MBD1 and MBD2 is reduced or absent in embryonic stem cells, which are known to be deficient in MeCP1 activity. MBD4 have homology to bacterial base excision repair DNA N-glycosylases/lyases. In some microsatellite unstable tumors MBD4 is mutated at an exonic polynucleotide tract.

Subcellular Location:
Nucleus speckle. Chromosome.

Tissue Specificity:
Widely expressed.

Similarity:
Contains 3 CXXC-type zinc fingers.
Contains 1 MBD (methyl-CpG-binding) domain.

Database links:

Entrez Gene: 4152 Human

Omim: 156535 Human

SwissProt: Q9UIS9 Human

Unigene: 405610 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天干夜天天夜天干天2004年 | 亚洲天堂一区二区三区四区 | 色综合久久无码中文字幕 | 18禁美女裸体网站无遮挡 | 丰满熟妇乱又伦在线无码视频 | 日韩中文字幕免费在线观看 | 亚洲国产精品久久久久婷婷老年 | 国产乱人伦真实精品视频 | www.九色.com| 亚洲国产成人自拍 | 91精品国产91久久久久久黑人 | 日韩美女在线 | 久久精品国产亚洲blacked | 精品动漫无码一区二 | 欧美日本一区视频免费 | 日本一区精品视频 | 一本到国产在线精品国内 | 欧美1区2区在线观看 | 香蕉成人影院 | 亚洲成人资源在线 | 亚洲国产精品美女久久久久 | JAPANESE50MATURE亂倫 | 久操av在线播放 | 99久久精品费精品 | 春药玩弄少妇高潮吼叫 | 一级毛片影视 | 一区二区三区香蕉视频 | 538国产精品 | 九色腾高清| 少妇的肉体迎合快乐 | 延禧攻略在线看 | 天天操天天干天天曰 | 国产成人福利在线观看 | 黑人巨茎大战欧美白妇免费 | 四季久久免费一区二区三区四区 | 久久精品免费看国产免费软件 | 欧美xxxx性bbbbb喷水 | 嫩B人妻精品一区二区三区 avav国产 | 国内一级大片 | 久久久精品午夜免费不卡 | 色综合激情无码中文字幕 |