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Rabbit Anti-Reticulon 1/BF594 Conjugated antibody (bs-11798R-BF594)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11798R-BF594
英文名稱 Rabbit Anti-Reticulon 1/BF594 Conjugated antibody
中文名稱 BF594標記的神經內分泌特異性蛋白抗體
別    名 MGC133250; Neuroendocrine specific protein; NSP; Reticulon 1; Reticulon1; Reticulon1A; RTN 1; RTN1; RTN1 protein; RTN1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  神經生物學  腫瘤細胞生物標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 84kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Reticulon 1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. This gene is considered to be a specific marker for neurological diseases and cancer, and is a potential molecular target for therapy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]

Function:
May be involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells.

Subunit:
Interacts with NDRG1.

Subcellular Location:
Endoplasmic reticulum membrane; Multi-pass membrane protein.

Tissue Specificity:
Expressed in neural and neuroendocrine tissues and cell cultures derived therefrom. Expression of isoform RTN1-C is strongly correlated with neuronal differentiation.

Post-translational modifications:
Isoforms RTN1-A and RTN1-B are phosphorylated.

Similarity:
Contains 1 reticulon domain.

Database links:

Entrez Gene: 6252 Human

Entrez Gene: 116644 Rat

Omim: 600865 Human

SwissProt: Q16799 Human

SwissProt: Q64548 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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