超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久草在线视频看看,色吊丝视频,欧美性不卡
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Acetyl Coenzyme A carboxylase alpha/Biotin Conjugated antibody (bs-11912R-Bio)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11912R-Bio
英文名稱 Rabbit Anti-Acetyl Coenzyme A carboxylase alpha/Biotin Conjugated antibody
中文名稱 生物素標記的乙酰輔酶A羧化酶1ACCα抗體
別    名 ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC-alpha; ACC1; ACC1; ACCA; Acetyl Coenzyme A; Biotin carboxylase; ACACA_MOUSE; Acetyl Coenzyme A carboxylase alpha; ACACA_RAT; Acetyl-CoA carboxylase 1; ACC-alpha.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  轉錄調節因子  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 WB=1:50-200 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 266kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACACA
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Subunit:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.

Post-translational modifications:
Phosphorylation on Ser-1263 is required for interaction with BRCA1.

DISEASE:
Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:200350]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.

Similarity:
Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.

Database links:

Entrez Gene: 31 Human

Entrez Gene: 32 Human

Entrez Gene: 107476 Mouse

Entrez Gene: 60581 Rat

Omim: 200350 Human

SwissProt: O00763 Human

SwissProt: Q13085 Human

SwissProt: Q5SWU9 Mouse

SwissProt: P11497 Rat

Unigene: 160556 Human

Unigene: 234898 Human

Unigene: 31374 Mouse

Unigene: 163753 Rat

Unigene: 217177 Rat

Unigene: 44372 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 九色国产在线观看 | 亚洲香蕉久久 | 日本免费无遮挡吸乳视频网站 | 欧美三区二区一区 | 人妻有码av中文字幕久久琪 | 8k8k成人网| 97久久亚洲| 亚洲a黄 | 精品欧美在线观看 | 国产97超碰 | 国产妇女馒头高清泬20P多毛 | 97精品国产97久久久久久久久久久久 | 91热视频在线观看 | 亚洲国产精品久久久久久 | 欧美一页 | 亚洲一区二区三区尿失禁 | 中文字幕按摩做爰 | 黄频视频在线观看 | 日本一区二区三区久久久久 | 综合激情久久综合激情 | 欧美第一在线视频 | 青青青视频香蕉在线观看视频 | 国产精品成人麻烦视频 | 国产精品免费看久久久软件 | 国产伦精品一区二区三区综合网 | 亚洲AV午夜成人片 | 久久亚洲AV永久无码精品 | 日本乳首の奶水在线观看视频 | 丝袜老师张开腿任我玩弄 | 相泽南av日韩在线 | 成年免费观看视频 | 婷婷激情综合五月俺也去看 | 91福利精品第一导航禁漫天堂 | aV性色在线乱叫 | 国产日韩乱码精品一区二区 | 亚洲最大的av网站 | 好紧好滑好湿好爽免费视频 | 天天天天天操 | 人成久久 | 亚洲一二三传媒有限公司 | 好硬好湿好爽再深一点动态图视频 |