超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
九九热有精品,中文字幕在线观看二区,精品美女av
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Acetyl Coenzyme A carboxylase alpha/BF555 Conjugated antibody (bs-11912R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11912R-BF555
英文名稱 Rabbit Anti-Acetyl Coenzyme A carboxylase alpha/BF555 Conjugated antibody
中文名稱 BF555標記的乙酰輔酶A羧化酶1ACCα抗體
別    名 ACAC; ACACA; ACACA; ACACA_HUMAN; ACC alpha; ACC-alpha; ACC1; ACC1; ACCA; Acetyl Coenzyme A; Biotin carboxylase; ACACA_MOUSE; Acetyl Coenzyme A carboxylase alpha; ACACA_RAT; Acetyl-CoA carboxylase 1; ACC-alpha.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  信號轉導  轉錄調節因子  激酶和磷酸酶  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Rat,  (predicted: Mouse, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 266kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human ACACA
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Acetyl-CoA carboxylase (ACC) is a complex multifunctional enzyme system. ACC is a biotin-containing enzyme which catalyzes the carboxylation of acetyl-CoA to malonyl-CoA, the rate-limiting step in fatty acid synthesis. There are two ACC forms, alpha and beta, encoded by two different genes. ACC-alpha is highly enriched in lipogenic tissues. The enzyme is under long term control at the transcriptional and translational levels and under short term regulation by the phosphorylation/dephosphorylation of targeted serine residues and by allosteric transformation by citrate or palmitoyl-CoA. Multiple alternatively spliced transcript variants divergent in the 5' sequence and encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Function:
Catalyzes the rate-limiting reaction in the biogenesis of long-chain fatty acids. Carries out three functions: biotin carboxyl carrier protein, biotin carboxylase and carboxyltransferase.

Subunit:
Monomer, homodimer, and homotetramer. Can form filamentous polymers. Interacts in its inactive phosphorylated form with the BRCT domains of BRCA1 which prevents ACACA dephosphorylation and inhibits lipid synthesis. Interacts with MID1IP1; interaction with MID1IP1 promotes oligomerization and increases its activity.

Subcellular Location:
Cytoplasm.

Tissue Specificity:
Expressed in brain, placental, skeletal muscle, renal, pancreatic and adipose tissues; expressed at low level in pulmonary tissue; not detected in the liver.

Post-translational modifications:
Phosphorylation on Ser-1263 is required for interaction with BRCA1.

DISEASE:
Defects in ACACA are a cause of acetyl-CoA carboxylase 1 deficiency (ACACAD) [MIM:200350]; also known as ACAC deficiency or ACC deficiency. An inborn error of de novo fatty acid synthesis associated with severe brain damage, persistent myopathy and poor growth.

Similarity:
Contains 1 ATP-grasp domain.
Contains 1 biotin carboxylation domain.
Contains 1 biotinyl-binding domain.
Contains 1 carboxyltransferase domain.

Database links:

Entrez Gene: 31 Human

Entrez Gene: 32 Human

Entrez Gene: 107476 Mouse

Entrez Gene: 60581 Rat

Omim: 200350 Human

SwissProt: O00763 Human

SwissProt: Q13085 Human

SwissProt: Q5SWU9 Mouse

SwissProt: P11497 Rat

Unigene: 160556 Human

Unigene: 234898 Human

Unigene: 31374 Mouse

Unigene: 163753 Rat

Unigene: 217177 Rat

Unigene: 44372 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 人妻无码中文字幕一区二区三区 | 四虎久久久久 | 日本黄色免费在线观看 | 国产免费AV片在线观看播放器 | 亚洲欧美日韩中文字幕在线一区 | 91免费看.| 国产乡下妇女三片 | 久久精品最新地址 | 欧美狠狠操| 韩日视频一区二区 | 太深太粗太爽太猛了视频免费观看 | 国产日本在线 | 狠狠躁夜夜躁xxxxaaaa | 国产亚洲精品无 | 欧美国产视频一区二区 | 亚洲欧美激情视频 | 在线观看免费av片 | 亚洲精品乱码久久久久久9色 | 日韩中出 | 17C精品麻豆一区二区免费 | 在线亚洲欧美日韩精品专区 | 久热在线视频 | 色就是色网址 | 国产免费无遮挡吸乳视频 | 人和牛交VIDE欧美 | 野花社区观看免费观看视频 | 国产成人久久AV免费看 | 欧美一级淫片a | 福利一区和二区 | 国产成年人小视频 | 日韩中文字幕永久 | 国产九一精品 | 中文字幕在线播放不卡 | 暖暖免费高清日本社区在线观看 | 噼里啪啦2在线观看免费 | 91啦丨porny丨国产 | 国产亚洲精品自在久久蜜TV | 国产va免费精品观看 | 免费XXXX大片 | 日本日本熟妇中文在线视频 | 国产精品久久久久久久久免费桃花 |