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Rabbit Anti-Neurabin 1/HRP Conjugated antibody (bs-11988R-HRP)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-11988R-HRP
英文名稱 Rabbit Anti-Neurabin 1/HRP Conjugated antibody
中文名稱 辣根過氧化物酶標記的神經組織特異性F肌動蛋白結合蛋白抗體
別    名 FLJ20068; KIAA1222; NEB1_HUMAN; Neurabin I; Neurabin-1; Neurabin-I; Neurabin1; Neurabin-1; NeurabinI; Neurabin1; Neural tissue specific F actin binding protein I; Neural tissue-specific F-actin-binding protein I; NRB 1; NRB I; NRB1; NRBI; PPP1R9A; Protein phosphatase 1 regulatory (inhibitor) subunit 9A; Protein phosphatase 1 regulatory subunit 9A.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  轉運蛋白  細胞骨架  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Rabbit, Sheep, )
產品應用 WB=1:500-2000 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 123kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human Neurabin 1/PPP1R9A (115-165aa)
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is imprinted, and located in a cluster of imprinted genes on chromosome 7q12. This gene is transcribed in both neuronal and multiple embryonic tissues, and it is maternally expressed mainly in embryonic skeletal muscle tissues and biallelically expressed in other embryonic tissues. The protein encoded by this gene includes a PDZ domain and a sterile alpha motif (SAM). It is a regulatory subunit of protein phosphatase I, and controls actin cytoskeleton reorganization. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2009]

Function:
Binds to actin filaments (F-actin) and shows cross-linking activity. Binds along the sides of the F-actin. May be involved in neurite formation. Inhibits protein phosphatase 1-alpha activity.

Subcellular Location:
Cytoplasm.

Similarity:
Contains 1 PDZ (DHR) domain.
Contains 1 SAM (sterile alpha motif) domain.

Database links:

Entrez Gene: 55607 Human

Entrez Gene: 243725 Mouse

Entrez Gene: 84685 Rat

Omim: 602468 Human

SwissProt: Q9ULJ8 Human

SwissProt: O35867 Rat

Unigene: 21816 Human

Unigene: 10849 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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