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      Rabbit Anti-5HT1D Receptor/RBITC Conjugated antibody (bs-12046R-RBITC)
      訂購熱線:400-901-9800
      訂購郵箱:sales@bioss.com.cn
      訂購QQ:  400-901-9800
      技術支持:techsupport@bioss.com.cn
      說 明 書: 100ul  
      100ul/2980.00元
      大包裝/詢價
      產(chǎn)品編號 bs-12046R-RBITC
      英文名稱 Rabbit Anti-5HT1D Receptor/RBITC Conjugated antibody
      中文名稱 羅丹明(RBITC)標記的5-羥色胺受體1D抗體
      別    名 SR-1D; 5 HT 1D alpha; 5 HT 1D; 5 HT1B; 5 HT1D; 5HT1D; 5 hydroxytryptamine (serotonin) receptor 1B; 5 hydroxytryptamine (serotonin) receptor 1D G protein coupled; 5 hydroxytryptamine 1B receptor (5 HT 1B) (Serotonin receptor) (5 HT 1D beta) (Serotonin 1D beta receptor) (S12); 5 hydroxytryptamine receptor 1D; HT1DA; HTR1D; HTR1D2; HTR1DA; HTRL; RDC4; S12; Serotonin receptor 1D; 5HT1D_HUMAN.  
      規(guī)格價格 100ul/2980元 購買        大包裝/詢價
      說 明 書 100ul  
      研究領域 神經(jīng)生物學  細胞膜受體  G蛋白偶聯(lián)受體  新陳代謝  G蛋白信號  
      抗體來源 Rabbit
      克隆類型 Polyclonal
      交叉反應 Mouse,  (predicted: Human, Rat, Rabbit, )
      產(chǎn)品應用 ICC=1:50-200 IF=1:50-200 
      not yet tested in other applications.
      optimal dilutions/concentrations should be determined by the end user.
      分 子 量 42kDa
      性    狀 Lyophilized or Liquid
      濃    度 1mg/ml
      免 疫 原 KLH conjugated synthetic peptide derived from human 5HT1D Receptor/SR-1D
      亞    型 IgG
      純化方法 affinity purified by Protein A
      儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
      保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
      產(chǎn)品介紹 background:
      The members of the G-protein-coupled receptor family are distinguished by their slow transmitting response to ligand binding. These seven transmembrane proteins include the adrenergic, serotonin and dopamine receptors. The effect of the signaling molecule can be excitatory or inhibitory depending on the type of receptor to which it binds. b-adrenergic bound to adrenaline activates adenylyl cyclase, while a2-adrenergic receptor bound to adrenaline inhibits adenylyl cyclase. Like the a2-adrenergic receptor, serotonin receptor functions are also mediated by G proteins that inhibit the activity of adenylyl cyclase. The serotonin receptors have been classified into several categories, designated SR-1–7 (5HT1–7). Subtypes within the SR-1 group include SR-1A, -1B, -1D, -1E and -1F.

      Function:
      This is one of the several different receptors for 5-hydroxytryptamine (serotonin), a biogenic hormone that functions as a neurotransmitter, a hormone, and a mitogen. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity.

      Subcellular Location:
      Cell membrane; Multi-pass membrane protein

      Similarity:
      Belongs to the G-protein coupled receptor 1 family.

      Database links:

      Entrez Gene: 3352 Human

      Entrez Gene: 15552 Mouse

      Entrez Gene: 25323 Rat

      Omim: 182133 Human

      SwissProt: P28221 Human

      SwissProt: Q61224 Mouse

      SwissProt: P28565 Rat

      Unigene: 121482 Human

      Unigene: 40573 Mouse

      Unigene: 34834 Rat




      Important Note:
      This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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