超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
亚洲高清视频免费看,国产成人无码aa精品一区,国产无色aaa
Rabbit Anti-GARP/Cy3 Conjugated antibody (bs-12093R-Cy3)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12093R-Cy3
英文名稱 Rabbit Anti-GARP/Cy3 Conjugated antibody
中文名稱 Cy3標(biāo)記的環(huán)磷酸鳥苷門控通道蛋白CNG4抗體
別    名 CNCG2; CNCG3L; CNCG4; CNG 4; CNG-4; CNG channel 4; CNG channel beta 1; CNG4; CNGB 1; CNGB1; CNGB1B; Cyclic nucleotide gated cation channel 4; Cyclic nucleotide gated cation channel; Cyclic nucleotide gated cation channel beta 1; Cyclic nucleotide gated cation channel gamma; Cyclic nucleotide gated cation channel modulatory subunit; Cyclic nucleotide gated channel (photoreceptor) cGMP gated 3 (gamma) like; Cyclic nucleotide gated channel beta 1; GAR1; Glutamic acid rich protein; RCNC2; RCNCb; RCNCbeta; RP45; CNGB1_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說 明 書 100ul  
研究領(lǐng)域 神經(jīng)生物學(xué)  通道蛋白  細(xì)胞膜受體  G蛋白偶聯(lián)受體  G蛋白信號(hào)  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 140kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CNG4
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).

Function:
GARP is a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Defects in GARP are the cause of retinitis pigmentosa type 45 (RP45). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Subunit:
Heterooligomeric complex with CNGA1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Prominently expressed in retina.

DISEASE:
Defects in CNGB1 are the cause of retinitis pigmentosa type 45 (RP45) [MIM:613767]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB1 subfamily.
Contains 1 cyclic nucleotide-binding domain.

Database links:

Entrez Gene: 1258 Human

Entrez Gene: 333329 Mouse

Entrez Gene: 83686 Rat

Omim: 600724 Human

SwissProt: Q14028 Human

  • wissProt: O35788 Rat


  • Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
    通過國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
    通過國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
    京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
    主站蜘蛛池模板: 精品久久久久久久久久久久久久久久 | 国产精品第7页 | 出差我被公高潮A片久久 | 国产精品久久久久久久久侵犯 | 国产午夜视频免费 | 91成人免费 | 久久久精品一区AAA片 | 国产无套露脸视频在线观看 | 无码亚洲成A∧人片在线播放 | 极品少妇xxxx精品少妇偷拍 | 狠狠操在线视频 | 国产尤物在线观看yw | 操人网站 | 国内精品视频一区二区三区八戒 | jizz大全日本护士喷奶水 | 91九色最新地址 | 亚洲无亚洲人成网站77777 | 国产精品亚洲一区在现观看 | 91久久国产综合久久91猫猫 | 欧美性猛交xxxx乱大交俱乐部 | 成人国产精品高清在线观看 | 久久伦理精品 | 国产人妻精品久久久久野外 | 免费在线a级片 | 超碰aⅴ人人做人人爽 | 国产1级毛片 | 五十路六十路老熟妇a片 | 国产精品av一区二区三区 | 欧美亚一区二区 | 国产成人片在线观看永久观看 | 成片人免费观看一级A片 | 国产中文字幕在线免费观看 | 亚洲免费视频一区 | 久久国产精品99精国产 | 在线观看免费毛片 | 亚洲人成人一区二区三区 | 日韩一区二区免费在线观看 | 人人干人人爱 | 黄色一级毛片儿 | 久久久精品免费视频 | 国内精品久久久久伊人av |