超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲一区二区三区高清视频,亚洲国产香蕉碰碰人人,日韩大片一区二区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GARP/BF488 Conjugated antibody (bs-12093R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12093R-BF488
英文名稱 Rabbit Anti-GARP/BF488 Conjugated antibody
中文名稱 BF488標記的環磷酸鳥苷門控通道蛋白CNG4抗體
別    名 CNCG2; CNCG3L; CNCG4; CNG 4; CNG-4; CNG channel 4; CNG channel beta 1; CNG4; CNGB 1; CNGB1; CNGB1B; Cyclic nucleotide gated cation channel 4; Cyclic nucleotide gated cation channel; Cyclic nucleotide gated cation channel beta 1; Cyclic nucleotide gated cation channel gamma; Cyclic nucleotide gated cation channel modulatory subunit; Cyclic nucleotide gated channel (photoreceptor) cGMP gated 3 (gamma) like; Cyclic nucleotide gated channel beta 1; GAR1; Glutamic acid rich protein; RCNC2; RCNCb; RCNCbeta; RP45; CNGB1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  通道蛋白  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 140kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CNG4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).

Function:
GARP is a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Defects in GARP are the cause of retinitis pigmentosa type 45 (RP45). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Subunit:
Heterooligomeric complex with CNGA1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Prominently expressed in retina.

DISEASE:
Defects in CNGB1 are the cause of retinitis pigmentosa type 45 (RP45) [MIM:613767]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB1 subfamily.
Contains 1 cyclic nucleotide-binding domain.

Database links:

Entrez Gene: 1258 Human

Entrez Gene: 333329 Mouse

Entrez Gene: 83686 Rat

Omim: 600724 Human

SwissProt: Q14028 Human

  • wissProt: O35788 Rat


  • Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
    通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
    通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
    京ICP備05066980號-1         京公網安備110107000727號
    主站蜘蛛池模板: 欧美丰满熟妇xxxx性 | 91麻豆精品国产91久久久使用方法 | 亚洲欧美成人一区二区 | 国产无套露脸视频在线观看 | 亚洲AV无码片区一区二区三区 | 好硬好湿好爽再深一点动态图视频 | 91视频污版 | 人人综合亚洲无线码另类 | 久久精品国产亚洲AV成人 | 歪歪爽蜜臀AV久久精品人人槡 | 国产一级一级理论片一区二区 | 国产视频一区二区在线播放 | 日本黄色一级片视频 | 国产高清精品二区 | 国产99视频精品免费观看9 | 欧美午夜精品久久久久久软件 | 中日韩在线观看 | 亚洲一区二区三区精品动漫 | 性猛aa久久久 | 久久久久亚洲AV无码永不 | 大量情侣在线偷拍小视频 | 韩国av片永久免费 | 欧美视频福利 | 欧美在线一二三 | 欧美日韩一区二区三区 | 怦然心动2在线观看免费高清 | 丰满熟妇乱又伦在线无码视频 | 国产毛片毛多水多的特级毛片 | 黑人巨大两根一起挤进a片视频 | 国产精品久久久久久久毛片 | 91精品国产一区二区三区在线 | 丰满少妇高潮叫久久国产 | 色综合天天综合高清 | 大学生寝室白袜自慰gay网站 | 少妇性BBB搡BBB爽爽爽视频 | 欧美性色黄大片 | 中文字幕乱码人妻系列 | 亚洲欧美日韩国产高清在线观看 | 91看片国产 | 久久久女人 | 日本在线不卡视频一二三区 |