超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
日韩在线观看高清,精品少妇一区二区三区日产乱码,亚洲久热
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-GARP/BF594 Conjugated antibody (bs-12093R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12093R-BF594
英文名稱 Rabbit Anti-GARP/BF594 Conjugated antibody
中文名稱 BF594標記的環磷酸鳥苷門控通道蛋白CNG4抗體
別    名 CNCG2; CNCG3L; CNCG4; CNG 4; CNG-4; CNG channel 4; CNG channel beta 1; CNG4; CNGB 1; CNGB1; CNGB1B; Cyclic nucleotide gated cation channel 4; Cyclic nucleotide gated cation channel; Cyclic nucleotide gated cation channel beta 1; Cyclic nucleotide gated cation channel gamma; Cyclic nucleotide gated cation channel modulatory subunit; Cyclic nucleotide gated channel (photoreceptor) cGMP gated 3 (gamma) like; Cyclic nucleotide gated channel beta 1; GAR1; Glutamic acid rich protein; RCNC2; RCNCb; RCNCbeta; RP45; CNGB1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 神經生物學  通道蛋白  細胞膜受體  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 140kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CNG4
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cyclic nucleotide-gated (CNG) cation channels are heteromeric complexes made up of principal alpha and modulatory beta subunits (1,2). The alpha subunits consist of CNG1-3 and form functional cation channels by themselves (1,2). The beta subunits consist of CNG4-6 and, unlike the alpha subunits, do not form functional channels, but rather modify the properties of channels (1,2). CNG channels are essential components of olfactory and visual transduction (1,2). In olfactory neurons, CNG2, CNG4.3 and CNG5 form Ca2+ permeable channels, which open and depolarize the cell in response to cAMP (1-3). In rod photoreceptors, CNG1 and CNG4.1 combine to form Ca ion permeable channels, which give rise to a current in response to cGMP (1-3). CNG3 and CNG6 are expressed in cone receptors and may combine to form a native cGMP-activated channel (2,3). CNG channels have been implicated in other areas (4-6). CNG1 is also expressed in medium-sized and small-sized arteries, suggesting a role for CNG in the regulation of arterial blood pressure and of blood supply to different regions (4). CNG1, CNG4.1 and CNG4.2 have been detected in the rat pineal gland (5). CNG2, CNG4.3 and CNG5 are present in GT1 cell lines and may play a role in the secretion of gonadotropin-releasing hormone (6).

Function:
GARP is a subunit of cyclic nucleotide-gated (CNG) channels, nonselective cation channels, which play important roles in both visual and olfactory signal transduction. When associated with CNGA1, it is involved in the regulation of ion flow into the rod photoreceptor outer segment (ROS), in response to light-induced alteration of the levels of intracellular cGMP. Defects in GARP are the cause of retinitis pigmentosa type 45 (RP45). RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Subunit:
Heterooligomeric complex with CNGA1.

Subcellular Location:
Membrane; Multi-pass membrane protein.

Tissue Specificity:
Prominently expressed in retina.

DISEASE:
Defects in CNGB1 are the cause of retinitis pigmentosa type 45 (RP45) [MIM:613767]. RP leads to degeneration of retinal photoreceptor cells. Patients typically have night vision blindness and loss of midperipheral visual field. As their condition progresses, they lose their far peripheral visual field and eventually central vision as well.

Similarity:
Belongs to the cyclic nucleotide-gated cation channel (TC 1.A.1.5) family. CNGB1 subfamily.
Contains 1 cyclic nucleotide-binding domain.

Database links:

Entrez Gene: 1258 Human

Entrez Gene: 333329 Mouse

Entrez Gene: 83686 Rat

Omim: 600724 Human

SwissProt: Q14028 Human

  • wissProt: O35788 Rat


  • Important Note:
    This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
    版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
    通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
    通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
    京ICP備05066980號-1         京公網安備110107000727號
    主站蜘蛛池模板: 三级国产在线观看 | 精品人妻系列无码人妻免费视频 | 日韩卡一卡二无线乱码新区仙踪林 | 精品国产91亚洲一区二区三区婷婷 | 日韩视频在线免费观看 | 天堂AV日韩AV无码AV | 伦人伦xxx国语对白 女同性恋一区 | 亚洲精品乱码久久久久久久 | 天天番号网 | 国色天香乱码区 | 蜜桃视频在线免费播放 | 久久青草网站 | 尤物AV无码色AV无码麻豆 | 欧洲影视字幕中文 | www.日日操 | 亚洲一区二区三区久久久 | 日本aaaa片毛片免费观看视频 | 亚洲无吗在线视频 | 中国熟妇毛茸茸xxxxx | 亚洲黄色小视频在线观看 | 亚洲欧美在线一区 | 国产AV无码专区亚洲AV潘金链 | 亚洲iv一区二区三区 | 91在线精品入口 | 在线看一区二区 | 国产精品186在线观看在线播放 | 国产精品无码免费热播 | 亚洲一区二区二区久久成人婷婷 | 综合色网站 | 久久亚洲AV无码精品色午夜 | 18毛片免费看 | 亚洲日本va中文字幕 | 久久AV无码精品人妻系列试探 | 黄色在线免费视频 | 免费网站毛片 | 日韩欧美国产综合 | 中文字幕人妻互换AV久久 | 亚洲国产日韩美 | 国产网红无码精品视频 | www.四虎影视| 欧美国产视频一区二区 |