超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢(xún)技術(shù)支持           掃碼咨詢(xún)技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
老司机成人精品视频lsj95,浴室边摸边吃奶边做边爱,污污在线视频
Rabbit Anti-CENPJ/RBITC Conjugated antibody (bs-13835R-RBITC)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢(xún)價(jià)
產(chǎn)品編號(hào) bs-13835R-RBITC
英文名稱(chēng) Rabbit Anti-CENPJ/RBITC Conjugated antibody
中文名稱(chēng) 羅丹明(RBITC)標(biāo)記的著絲粒蛋白J抗體
別    名 CENP-J; CENPJ; CENPJ_HUMAN; Centromere protein J; Centrosomal P4.1-associated protein; CPAP; LAG-3-associated protein; LAP; LIP1; LYST-interacting protein 1; MCPH6.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢(xún)價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  神經(jīng)生物學(xué)  信號(hào)轉(zhuǎn)導(dǎo)  轉(zhuǎn)錄調(diào)節(jié)因子  細(xì)胞分化  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 153kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CENPJ
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene encodes a protein that belongs to the centromere protein family. During cell division, this protein plays a structural role in the maintenance of centrosome integrity and normal spindle morphology, and it is involved in microtubule disassembly at the centrosome. This protein can function as a transcriptional coactivator in the Stat5 signaling pathway, and also as a coactivator of NF-kappaB-mediated transcription, likely via its interaction with the coactivator p300/CREB-binding protein. Mutations in this gene are associated with primary autosomal recessive microcephaly, a disorder characterized by severely reduced brain size and mental retardation. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012]

Function:
Plays an important role in cell division and centrosome function by participating in centriole duplication. Inhibits microtubule nucleation from the centrosome.

Subcellular Location:
Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > centrosome > centriole. Localized within the center of microtubule asters. During centriole biogenesis, it is concentrated within the proximal lumen of both parental centrioles and procentrioles.

Post-translational modifications:
Phosphorylation at Ser-589 and Ser-595 by PLK2 is required for procentriole formation and centriole elongation. Phosphorylation by PLK2 oscillates during the cell cycle: it increases at G1/S transition and decreases during the exit from mitosis. Phosphorylation at Ser-595 is also mediated by PLK4 but is not a critical step in PLK4 function in procentriole assembly.

DISEASE:
Defects in CENPJ are the cause of microcephaly primary type 6 (MCPH6) [MIM:608393]. A disorder defined as a head circumference more than 3 standard deviations below the age-related mean. Brain weight is markedly reduced and the cerebral cortex is disproportionately small. Despite this marked reduction in size, the gyral pattern is relatively well preserved, with no major abnormality in cortical architecture. Primary microcephaly is further defined by the absence of other syndromic features or significant neurological deficits.
Defects in CENPJ are the cause of Seckel syndrome type 4 (SCKL4) [MIM:613676].
SCKL4 is a rare autosomal recessive disorder characterized by proportionate dwarfism of prenatal onset associated with low birth weight, growth retardation, severe microcephaly with a bird-headed like appearance, and mental retardation.

Similarity:
Belongs to the TCP10 family.

Database links:

Entrez Gene: 55835 Human

Entrez Gene: 219103 Mouse

Omim: 609279 Human

SwissProt: Q9HC77 Human

SwissProt: Q569L8 Mouse

Unigene: 513379 Human

Unigene: 533828 Human

Unigene: 741581 Human

Unigene: 212525 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 久久男人AV资源网站 | 插插插插插插综合 | 国产不卡一区二区在线观看 | 国产女厕偷窥系列在线视频 | 亚洲精品18日本一区久久 | 男人的天堂AV高清在线 | 精品国产一区二区三区久久久樱花 | 欧美A级毛欧美1级A大片 | 日本熟妇无码色视频在线观看 | 亚洲二区三区不卡 | 欧美人牲口杂交在线播放免费 | 久久棈精品久久久久久噜噜 | av免费黄色 | 国产精品一区在线观看 | 深夜放纵内射少妇 | 国产精品性爱亚洲av性爱 | youjizz中国少妇 | 久久成人人人人精品欧 | 97超碰精品成人国产 | 天天做天天爱夜夜爽导航 | 日韩伦理中文字幕 | 亚洲一区二区三区视频播放 | 免费观看蜜桃视频www | 日本网站免费观看 | 亚洲一区二区三区精品动漫 | 无限在线观看片免费视频 | 国产精品久久久久久日本 | 激情人妻绿帽王八系列 | 国产精品视频免费网站 | 免费的性视频越黄越好 | 国产精彩乱子真实视频 | 浓精喷进老师黑色丝袜 | 精品美女久久久久 | 亚洲一区二区三区无码久久 | 久久久久久国产一级毛片... | 亚洲一区二区三区中文字幕在线 | 草在线视频 | 香蕉网在线 | 精品国产一区二区三区久久久樱花 | 色99热久久偷拍 | vr成人片在线播放网站 |