超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
精品国产美女福到在线不卡,国产超碰人人爽人人做人人添,亚洲人成网站18禁止人
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-Pumilio 2/BF488 Conjugated antibody (bs-12246R-BF488)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12246R-BF488
英文名稱 Rabbit Anti-Pumilio 2/BF488 Conjugated antibody
中文名稱 BF488標記的PUM2蛋白抗體
別    名 FLJ36528; KIAA0235; MGC138251; MGC138253; PUM 2; Pum2; PUM2; PUMH2; Pumilio (Drosphila) homolog 2; Pumilio homolog 2 (Drosophila); Pumilio homolog 2; Pumilio2; PUM2_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 發育生物學  干細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 114kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from Human Pumilio 2
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Pumilio 2 is a sequence-specific RNA-binding protein that regulates translation and mRNA stability by binding mRNA targets. It supports proliferation and self-renewal of stem cells by regulating the translation of key transcripts. The Pumilio gene encodes proteins that are required for development of germ stem cells in one or both sexes. The Pumilio protein interacts with the human Nanos1 protein and this interaction may play a conserved role in germ cell development. Pumilio 2 is highly expressed in testis and ovary and at lower levels in brain, heart, kidney, liver, muscle, placenta, intestine and stomach. It is also expressed in stem cells, germ cells and in most fetal tissues.

Function:
Pumilio 2, a human homolog of Pumilio, a protein required to maintain germ line stem cells in Drosophila and Caenorhabditis elegans, forms a stable complex with DAZ through the same functional domain required for RNA binding, protein-protein interactions and rescue of Pumilio mutations in flies. Pumilio 2 is expressed predominantly in human embryonic stem cells and germ cells and colocalizes with DAZ and DAZL in germ cells. Pumilio 2 is a component of conserved cellular machinery that may be required for germ cell development.

Subunit:
Homodimer; homodimerizes in vitro. Interacts with DAZ, DAZL and NANOS1 via its pumilio repeats. Binds to a RNA consensus sequence, that is related to the Nanos Response Element (NRE), a 16 bp sequence found in the 3'-UTR of the Drosophila hb mRNA. Also binds to the NRE. Interacts with NANOS3 (By similarity). Interacts with SNAPIN.

Subcellular Location:
Cytoplasm (Probable). Cytoplasmic granule (By similarity). Cytoplasm, perinuclear region. Note=The cytoplasmic granules are stress granules which are a dense aggregation in the cytosol composed of proteins and RNAs that appear when the cell is under stress. Co-localizes with NANOS3 in the stress granules (By similarity). Co-localizes with NANOS1 and SNAPIN in the perinuclear region of germ cells.

Tissue Specificity:
Expressed in male germ cells of adult testis (at protein level). Highly expressed in testis and ovary. Predominantly expressed in stem cells and germ cells. Expressed at lower level in brain, heart, kidney, liver, muscle, placenta, intestine and stomach Expressed in cerebellum, corpus callosum, caudate nucleus, hippocampus, medulla oblongata and putamen. Expressed in all fetal tissues tested.

Similarity:
Contains 1 PUM-HD domain.
Contains 8 pumilio repeats.

Database links:
UniProtKB/Swiss-Prot: Q8TB72.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 久久精品爱看无码免费视频 | 免费观看成人欧美WWW色 | 亚洲欧美综合在线一区 | 福利姬国产在线观看免费 | 亚洲片在线观看 | 中日韩在线观看 | 国产国语一级毛片 | 国产无遮挡又黄又大又爽 | 无码专区国产精品视频 | 久久久亚洲欧洲日产国码是AV | 性巴克一键去除衣物 | 中文字幕佐山爱一区二区 | 久久精品一区二区三区日韩 | 精品人妻系列无码天堂 | 欧美日韩a级片 | 91大神免费观看 | 人人干夜夜 | 无套内谢少妇毛片免费看 | 夜夜草天天草 | 一本色道精品久久一区二区三区 | 狠狠躁日日躁狂躁夜夜躁av | 欧美激情成人在线 | 久久久999久久久 | 日本黄色片免费观看 | 国产精品啪一品二区三区粉嫩 | 免费又黄又爽1000禁片 | 毛片成人免费看A片 | 99国产精品久久久久久久夜 | 亚洲av人人夜夜澡人人 | 午夜久久久精品 | 日本高清VA在线播放 | 二人午夜免费观看在线视频 | 免费观看无遮挡WWW的视频 | bb日韩美女预防毛片视频 | 爽爽窝窝午夜精品一区二区 | 特黄AAAAAAA片免费视频 | 三级黄色理论片 | 亚洲国产日韩欧美 | 亚洲高清国产拍精品影院 | 女人天堂在线a在线 | 亚洲高清无码在线观看 |