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Rabbit Anti-COQ3/BF488 Conjugated antibody (bs-13985R-BF488)
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說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13985R-BF488
英文名稱 Rabbit Anti-COQ3/BF488 Conjugated antibody
中文名稱 BF488標記的線粒體COQ3抗體
別    名 3 4 dihydroxy 5 hexaprenylbenzoate methyltransferase; bA9819.1; Coenzyme Q3 homolog methyltransferase (S. cerevisiae); Coenzyme Q3 homolog methyltransferase (yeast); Coenzyme Q3 homolog methyltransferase; COQ 3; DHHB methyltransferase; DHHB MT; DHHB MTase; DHHBMT; DHHBMTASE; Dihydroxyhexaprenylbenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase; Hexaprenyldihydroxybenzoate methyltransferase mitochondrial; Methyltransferase COQ3; OTTHUMP00000016892; UG0215E05.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  細胞類型標志物  新陳代謝  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 41kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human COQ3
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Ubiquinone, also known as coenzyme Q, or Q, is a critical component of the electron transport pathways of both eukaryotes and prokaryotes (Jonassen and Clarke, 2000 [PubMed 10777520]). This lipid consists of a hydrophobic isoprenoid tail and a quinone head group. The tail varies in length depending on the organism, but its purpose is to anchor coenzyme Q to the membrane. The quinone head group is responsible for the activity of coenzyme Q in the respiratory chain. The S. cerevisiae COQ3 gene encodes an O-methyltransferase required for 2 steps in the biosynthetic pathway of coenzyme Q. This enzyme methylates an early coenzyme Q intermediate, 3,4-dihydroxy-5-polyprenylbenzoic acid, as well as the final intermediate in the pathway, converting demethyl-ubiquinone to coenzyme Q. The COQ3 gene product is also capable of methylating the distinct prokaryotic early intermediate 2-hydroxy-6-polyprenyl phenol.[supplied by OMIM, Mar 2008]

Function:
COQ3 (Coenzyme Q3 homolog, methyltransferase) is an O-methyltransferase essential in the biosynthetic pathway of coenzyme Q (ubiquinone).

Subcellular Location:
Mitochondrion matrix.

Similarity:
Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Database links:

Entrez Gene: 51805 Human

Omim: 605196 Human

SwissProt: Q9NZJ6 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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