超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
久成人免费精品xxx,国产乱一区,东京热男人aV天堂
Rabbit Anti-CDON/HRP Conjugated antibody (bs-12323R-HRP)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書: 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-12323R-HRP
英文名稱 Rabbit Anti-CDON/HRP Conjugated antibody
中文名稱 辣根過(guò)氧化物酶標(biāo)記的細(xì)胞粘附分子相關(guān)蛋白/癌基因下調(diào)蛋白抗體
別    名 CDO; CDON; Cell adhesion molecule-related/down-regulated by oncogenes; CDON_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買        大包裝/詢價(jià)
說(shuō) 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  信號(hào)轉(zhuǎn)導(dǎo)  干細(xì)胞  細(xì)胞粘附分子  細(xì)胞表面分子  細(xì)胞膜蛋白  
抗體來(lái)源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) (predicted: Human, Mouse, Rat, Dog, Cow, Rabbit, Sheep, )
產(chǎn)品應(yīng)用 ELISA=1:100-1000 IHC-P=1:50-200 IHC-F=1:50-200 ICC=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 136kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CDON
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
Cell adhesion molecule-related/down-regulated by oncogenes (CDO) and BOC (brother of CDO) are members of the immunoglobulin/fibronectin type III repeat family and act as cell surface receptors. CDO is a component of a cell-surface receptor complex which also contains BOC, NEO1, CTNNB1 and cadherins and which acts as a mediator of cell-cell interactions between muscle cells. CDO and BOC are single pass membrane proteins that play a role in myogenic cell differentiation. Together, CDO and BOC participate in a positive feedback loop with MyoD, a myogenic transcription factor. The 1,242 amino acid rat CDO protein has a 24 residue signal sequence, five Ig V-like repeats, a 25 residue membrane-spanning region, three FNIII-like repeats and a cytoplasmic region of 256 amino acids containing a proline-rich stretch. The human protein contains 1,225 amino acid residues and shares significant homology with the domain structures of the rat protein.

Function:
CDON (Cdo), which is implicated in myogenesis also has a role in human forebrain development. Holoprosencephaly (HPE), a common defect of human forebrain development, is associated with haploinsufficiency for genes encoding Sonic Hedgehog (SHH) pathway components. Cdo positiviely regulates SHH in multiple ways, including at signal reception and via a parallel mechanism required at the level of Gli transcription factors. Specific Cdo domains required for its promyogenic effect are dispensable for its Shh signaling role, suggesting that Cdo has multiple, independent functions.

Subunit:
Part of a complex that contains BOC, CDON, NEO1, cadherins and CTNNB1. Interacts with NTN3 (By similarity). Interacts with PTCH1 (By similarity). Interacts with GAS1 (By similarity).

Subcellular Location:
Cell Membrane

Post-translational modifications:
N-glycosylated (By similarity).

DISEASE:
Defects in CDON are the cause of holoprosencephaly type 11 (HPE11) [MIM:614226]. HPE11 is a structural anomaly of the brain, in which the developing forebrain fails to correctly separate into right and left hemispheres. Holoprosencephaly is genetically heterogeneous and associated with several distinct facies and phenotypic variability.

Similarity:
Contains 3 fibronectin type-III domains.
Contains 5 Ig-like C2-type (immunoglobulin-like) domains.

Database links:
UniProtKB/Swiss-Prot: Q4KMG0.2

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 久久婷婷国产综合精品 | 国产成人女人在线观看 | 欧美精品在线一区二区三区 | 久久aⅴ人妻少妇嫩草影院 脱了我奶罩亲我奶头好舒服 | 精品一区二区三区四区视频 | 6699性视频 | 少妇人妻H好紧 | 斗破苍穹年番在线观看 | 青草草免费视频 | 做爰丰满少妇1313 | 国产干干| 国内一级大片 | 黑人床戏| 亚洲成a人片在线不卡一二三区 | 就是色综合 | 久久精品国产www456c0m | 国产a级久久久 | 伊人网综合视频 | 亚洲国产成人私人影院tom | FREEZEFRAME丰满老妇 | 亚洲色,天堂网 | 免费操碰 | 无码专区视频中文字幕 | 亚洲熟啪啪偷拍 | 亚洲一区二区三区爽爽爽爽爽 | 久久久久久九九九 | 国产成年无码V片在线 | 亚洲精品影院在线 | 中国一级伦理片 | 日本欧美成人 | 狠狠插网站 | 日本天堂免费观看 | 正在播放一区二区 | 91精品无码一区二区 | 精品日本久久 | 美女视频免费是黄的网站高清 | 无码专区视频中文字幕 | 色网站在线观看 | 国产男女免费视频 | 在线观看的网站你懂的 | 天天干天天弄 |