超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
午夜视频大全,国产精品一区三区在线观看,麻豆影院在线播放
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-BCL9/BF555 Conjugated antibody (bs-12393R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12393R-BF555
英文名稱 Rabbit Anti-BCL9/BF555 Conjugated antibody
中文名稱 BF555標記的B淋巴細胞淋巴瘤因子9抗體
別    名 B-cell CLL/lymphoma 9; BCL 9; BCL-9; DLNB11; Legless homolog; B-cell CLL/lymphoma 9-like; LGS; BCL9_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  染色質和核信號  轉錄調節因子  淋巴細胞  b-淋巴細胞  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Rabbit, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 149kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human BCL9
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Bcl-9L is a 1,499 amino acid protein that localizes to the nucleus and contains a specialized C-terminal domain that is important for its overall activity. Expressed in breast tissue, as well as in eye, lung, prostate and various carcinomas, Bcl-9L functions as a transcriptional activator that forms a complex with Parafibromin and β-catenin and is thought promote the transcriptional activity of Parafibromin and enhance the neoplastic transforming activity of β-catenin. Bcl-9L exists as multiple alternatively spliced isoforms and is thought to be involved in tumorigenesis, possibly playing a role in tumor transformation and metastasis. The gene encoding Bcl-9L maps to human chromosome 11, which houses over 1,400 genes and comprises nearly 4% of the human genome. Jervell and Lange-Nielsen syndrome, Jacobsen syndrome, Niemann-Pick disease, hereditary angioedema and Smith-Lemli-Opitz syndrome are associated with defects in genes that maps to chromosome 11.

Function:
BCL9 is involved in signal transduction through the Wnt pathway. It promotes beta-catenin's transcriptional activity. BCL9 is associated with B-cell acute lymphoblastic leukemia. The overexpression of BCL9 may be of pathogenic significance in B-cell malignancies (referenced from swissprot and entrez gene).

Subunit:
Binds to beta-catenin (CTNNB1), PYGO1 and PYGO2.

Subcellular Location:
Nuclear

Tissue Specificity:
Detected at low levels in thymus, prostate, testis, ovary and small intestine, and at lower levels in spleen, colon and blood.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

DISEASE:
Note=A chromosomal aberration involving BCL9 is found in a patient with precusor B-cell acute lymphoblastic leukemia (ALL). Translocation t(1;14)(q21;q32). This translocation leaves the coding region intact, but may have pathogenic effects due to alterations in the expression level of BCL9. Several cases of translocations within the 3'-UTR of BCL9 have been found in B-cell malignancies.

Similarity:
Belongs to the BCL9 family.

Database links:
UniProtKB/Swiss-Prot: O00512.4

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 亚洲激情av在线 | 少妇爽到呻吟的视频 | 人妻无码AV中文系列久久兔费 | 日韩精品卡1卡二卡3卡四卡 | 97影院在线免费看 | 日本无码潮喷A片无码高潮 欧美变态另类人妖 | 99香蕉国产精品偷在线观看 | 人妻少妇精品视中文字幕国语 | 夜夜爽影院 | 欧美一区二区在线视频 | 绯色av一区二区三区免费看 | 成人性生交免费大片2 | 国产成人精品亚洲日本语言 | 久久女同精品一区二区 | 国产精品亚洲二区在线观看 | 欧美人与动人物姣配XXXX | 日本免费一区二区三区最新 | 性囗交免费视频观看 | 日本黄色片免费 | 国产一级在线播放 | 日本久久久久久级做爰片 | 91国自产精品中文字幕亚洲 | 色欲欲WWW成人网站 好男人社区WWW在线观看 | a中文字幕www| 特级毛片在线 | 国产精品综合AV一区二区国产馆 | 国产一区内射最近更新 | xxxxx日本69| 青青草原综合久久大伊人 | 97成人资源站 | 宅男噜噜噜66国产精品86 | 欧美三级欧美成人高清www | 亚洲国产成人久久综合一区久久久国产99 | 亚洲AV永久无码精品九之 | 少妇性色午夜淫片aaa播放5 | 国产一精品av一免费爽爽 | 狠狠躁夜夜躁人人爽超碰97香蕉 | 免费精品一区二区三区第35 | 91精品视频免费在线观看 | 精品成人免费一区二区不卡 | 欧美日韩一区二区在线视频播放 |