超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产激情无码视频在线播放,久久亚色,第一亚洲中文久久精品无码
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FRAT1/BF594 Conjugated antibody (bs-12434R-BF594)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12434R-BF594
英文名稱 Rabbit Anti-FRAT1/BF594 Conjugated antibody
中文名稱 BF594標記的原癌基因FRAT1抗體
別    名 FRAT 1; frequently rearranged in advanced T cell lymphomas; Frequently rearranged in advanced T-cell lymphomas; GSK 3 binding protein FRAT1; proto oncogene FRAT1; FRAT1_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 腫瘤  細胞生物  發育生物學  信號轉導  干細胞  淋巴細胞  t-淋巴細胞  表觀遺傳學  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 29kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FRAT1
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 癈 for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20癈. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 癈.
產品介紹 background:
FRAT1 and FRAT2 were originally characterized as proteins frequently rearranged in advanced T cell lymphoma, and they have since been identified as proto-oncogenes involved in tumorigenesis. These proteins share significant homology with the Xenopus glycogen synthase kinase-3 (xGSK-3) binding protein, which is designated GBP and is essential for the formation of the dorsal-ventral axis during embryonic development. Establishment of these embryonic axes is mediated by the Wnt intracellular signaling pathway. Wnt signaling is regulated in part by the activity of GSK-3, which phosphorylates and thereby facilitates the degradation of ?catenin. GBP binds to GSK-3 and inhibits this phosphorylation, resulting in the accumulation of ?catenin and the subsequent transcription of Wnt target genes. Like GBP, FRAT2 has been shown to bind xGSK-3, suggesting that FRAT1 and FRAT2 may be GSK-3 regulatory proteins.

Function:
The protein encoded by the FRAT1 gene belongs to the GSK-3-binding protein family. The protein inhibits GSK-3-mediated phosphorylation of beta-catenin and also positively regulates the Wnt signaling pathway. It may play a role in tumor progression and in lymphomagenesis.

Subunit:
Binds DVL1. Binds GSK-3 and prevent GSK-3-dependent phosphorylation.

Subcellular Location:
Cytoplasmic.

Post-translational modifications:
Phosphorylated (By similarity).

Similarity:
Belongs to the GSK-3-binding protein family.

Database links:
UniProtKB/Swiss-Prot: Q92837.3

Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 无码精品AV久久久奶水小说 | 国产精品涩涩涩视频网站 | 豪放女大兵在线 | 亞洲中文字幕第一 | 看亚洲黄色片 | 色碰av | 欧美激情在线观看一区二区三区 | 亚洲黄色国产 | 久热综合在线亚洲精品 | 免费无码高潮流白浆视频 | 欧美精品一区二区免费 | 99无码人妻一区二区三区免费 | 春药刺激国产老富婆露脸 | 涩狠狠狠狠色 | 国产强奷糟蹋漂亮邻居在线观看 | 久久成人免费网 | 成人免费网站视频ww破解版 | 久久青视频 | 一级黄色片久久 | 欧美A级理论片在线播放 | 91视频导航 | 日韩av成人在线观看 | 日本韩国国产 | 国产精品人妻无码久久久苍井空 | 张雨绮被揉到高潮下不了床 | 韩国一级片免费看 | 女人天堂一区二区三区 | 国产伦码精品一区二区三区 | 99热这里只有精品在线 | 亚洲码国产精品高潮在线 | av无码精品一区二区久久 | 亚洲国产综合精品中文第一 | 无码专区视频中文字幕 | 天堂av亚洲av一二三区 | 密臀av一区二区 | 亚洲天堂av网站 | 一区二区三区不人妻无码 | 亚洲美女在线播放 | 国产AV尤物一区二区三区 | 老司机深夜福利网站 | 久久精品一本一区人人 |