超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
野花日本韩国大全免费版6,中文字幕永久视频在线看,国产精品青青青在线观看
Rabbit Anti-phospho-Cytokeratin 8 (Ser431)/PE Conjugated antibody (bs-12920R-PE)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-12920R-PE
英文名稱 Rabbit Anti-phospho-Cytokeratin 8 (Ser431)/PE Conjugated antibody
中文名稱 PE標(biāo)記的磷酸化細胞角蛋白8抗體
別    名 Cytokeratin 8 (phospho S431); p-Cytokeratin 8 (phospho S431); card2; Cardiac autoantigen 2 120kD; CK 8; CK-8; ck8; Cyk 8; cyk8; CYKER; Cytokeratin endo A; Cytokeratin-8; Cytokeratin8; DreK8; EndoA; k0; CYK8; k2c8; K2C8_HUMAN; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; Keratin8; KO; Krt 2.8; Krt 8; krt8; KRT-8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產(chǎn)品類型 磷酸化抗體 
研究領(lǐng)域 腫瘤  細胞生物  免疫學(xué)  信號轉(zhuǎn)導(dǎo)  細胞類型標(biāo)志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Human, Mouse,  (predicted: Rat, Horse, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CK8 around the phosphorylation site of Ser431
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Function:
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Subunit:
Heterotetramer of two type I and two type II keratins. KRT8 associates with KRT18. Associates with KRT20. Interacts with HCV core protein and PNN. When associated with KRT19, interacts with DMD. Interacts with TCHP. Interacts with APEX1.

Subcellular Location:
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.

Tissue Specificity:
Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.

Post-translational modifications:
Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.

DISEASE:
Defects in KRT8 are a cause of cirrhosis (CIRRH) [MIM:215600].

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 3856 Human

Entrez Gene: 16691 Mouse

Entrez Gene: 25626 Rat

Omim: 148060 Human

SwissProt: P05787 Human

SwissProt: P11679 Mouse

SwissProt: Q10758 Rat

Unigene: 533782 Human

Unigene: 708445 Human

Unigene: 358618 Mouse

Unigene: 11083 Rat 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細胞角蛋白是一類與結(jié)構(gòu)相關(guān)的蛋白家族,其在上皮細胞中形成細胞骨架中間絲。CK8存在于某些正常腺上皮及其腫瘤,包括許多導(dǎo)管上皮和腺上皮,如結(jié)腸、胃、小腸、氣管的上皮和尿路上皮。CK8主要用于腺癌和導(dǎo)管癌的診斷,該抗體特異識別第23位絲氨酸磷酸化的CK8。
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 91靠逼软件| 天天搞夜夜 | 久久国产精选 | av片网站在线观看 | 久久精品免费看国产免费软件 | 国精品久久久久久久久久久58 | 成年人视频在线免费观看 | 国产精品v欧美精品v日韩精品v | 久久草草影视免费网 | 91操人 | 国产巨作麻豆欧美亚洲综合久久 | 亚洲不卡无码永久在线观看 | 好男人好资源神马在线观看 | 免费a级毛片无码a∨免费软件 | 久久er热在这里只有精品66 | 亚洲人成综合第一网 | 四虎免费入口 | 国产成人精品日本亚洲网站 | 人人干人人澡 | 黄色日本在线观看 | 国产精品久久久999 色婷婷av一区二区三区小说 | 一级久久久 | 噜噜色噜噜 | 粗大黑人巨精大战欧美成人 | 国产精品综合AV一区二区国产馆 | 啪啪玩小处雏女毛免费 | 开心色91 | 东京热无码AV在线 | 欧美亚洲另类图片 | 精品一级黄色片 | 精品久久久久久无码人妻蜜桃 | 99精品在线| 欧美精品一区二区三区久久久竹菊 | 人人草视频在线观看 | 筋肉雄汁gay雄汁外送网站 | 免费国产成人 | xxxx午夜 | 亚洲最大成人影院 | 裸体超大乳抖乳露双乳呻吟 | 人妻少妇精品视中文字幕国语 | 国产一区二区三区黄视频 |