超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
麻豆视频精品,黄页网站在线观看,www.一区二区.com
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Cytokeratin 8 (Ser431)/PE-Cy5.5 Conjugated antibody (bs-12920R-PE-Cy5.5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12920R-PE-Cy5.5
英文名稱 Rabbit Anti-phospho-Cytokeratin 8 (Ser431)/PE-Cy5.5 Conjugated antibody
中文名稱 PE-Cy5.5標記的磷酸化細胞角蛋白8抗體
別    名 Cytokeratin 8 (phospho S431); p-Cytokeratin 8 (phospho S431); card2; Cardiac autoantigen 2 120kD; CK 8; CK-8; ck8; Cyk 8; cyk8; CYKER; Cytokeratin endo A; Cytokeratin-8; Cytokeratin8; DreK8; EndoA; k0; CYK8; k2c8; K2C8_HUMAN; k8; Keratin 8; Keratin type ii cytoskeletal 8; Keratin, type II cytoskeletal 8; Keratin-8; Keratin8; KO; Krt 2.8; Krt 8; krt8; KRT-8; MGC118110; MGC174782; MGC53564; MGC85764; sb:cb186; Type-II keratin Kb8.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 腫瘤  細胞生物  免疫學  信號轉導  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse,  (predicted: Rat, Horse, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 53kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human CK8 around the phosphorylation site of Ser431
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
This gene is a member of the type II keratin family clustered on the long arm of chromosome 12. Type I and type II keratins heteropolymerize to form intermediate-sized filaments in the cytoplasm of epithelial cells. The product of this gene typically dimerizes with keratin 18 to form an intermediate filament in simple single-layered epithelial cells. This protein plays a role in maintaining cellular structural integrity and also functions in signal transduction and cellular differentiation. Mutations in this gene cause cryptogenic cirrhosis. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012].

Function:
Together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated muscle.

Subunit:
Heterotetramer of two type I and two type II keratins. KRT8 associates with KRT18. Associates with KRT20. Interacts with HCV core protein and PNN. When associated with KRT19, interacts with DMD. Interacts with TCHP. Interacts with APEX1.

Subcellular Location:
Cytoplasm. Nucleus, nucleoplasm. Nucleus matrix.

Tissue Specificity:
Observed in muscle fibers accumulating in the costameres of myoplasm at the sarcolemma membrane in structures that contain dystrophin and spectrin. Expressed in gingival mucosa and hard palate of the oral cavity.

Post-translational modifications:
Phosphorylation on serine residues is enhanced during EGF stimulation and mitosis. Ser-74 phosphorylation plays an important role in keratin filament reorganization.
O-glycosylated. O-GlcNAcylation at multiple sites increases solubility, and decreases stability by inducing proteasomal degradation.
O-glycosylated (O-GlcNAcylated), in a cell cycle-dependent manner.

DISEASE:
Defects in KRT8 are a cause of cirrhosis (CIRRH) [MIM:215600].

Similarity:
Belongs to the intermediate filament family.

Database links:

Entrez Gene: 3856 Human

Entrez Gene: 16691 Mouse

Entrez Gene: 25626 Rat

Omim: 148060 Human

SwissProt: P05787 Human

SwissProt: P11679 Mouse

SwissProt: Q10758 Rat

Unigene: 533782 Human

Unigene: 708445 Human

Unigene: 358618 Mouse

Unigene: 11083 Rat 



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

細胞角蛋白是一類與結構相關的蛋白家族,其在上皮細胞中形成細胞骨架中間絲。CK8存在于某些正常腺上皮及其腫瘤,包括許多導管上皮和腺上皮,如結腸、胃、小腸、氣管的上皮和尿路上皮。CK8主要用于腺癌和導管癌的診斷,該抗體特異識別第23位絲氨酸磷酸化的CK8。
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 天天干天天操天天玩 | 在线观看的网站你懂的 | 久久国产色av | 亚洲午夜国产成人 | 最新黄色在线 | 国产尤物在线视频 | 日韩无砖专区一中文字目 | 正在播放白领少妇第一次 | 成人av一区二区在线观看 | 91视频网页版 | 欧美性猛交xxxx偷拍洗澡 | 222亚洲伊人成无码综合网 | 四虎免费紧急入口观看 | 伦理片一级二级片 | 国产亚洲美女精品久久久2020 | 人妻少妇不满足中文字幕 | 欧美性淫爽ww久久久久无 | 日本极品 | 色午夜婷婷 | 国产精品成人免费一区久久羞羞 | 一本色道久久亚洲综合精品蜜桃 | 成人国产精品入口免费视频 | 亚洲小视频在线 | 日韩在线一级片 | 波多野结衣中文字幕在线视频 | 91麻豆国产福利在线观看宅福利 | 操操影视| 久久久久久久一区二区 | 久久久久久久久99 | 成人国产精品高清在线观看 | 国产精品嫩草影院一二三区入口 | 少妇高潮无遮挡毛片免费播放 | 狠狠插久久综合网最新章节 | www成人精品 | 日韩欧美在线播放视频 | 亚洲最大的av网站 | 91麻豆免费在线观看 | 午夜影院在线观看版 | 国产高清激情在线观看 | 日本色www | 大地网资源在线观看免费高清 |