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Rabbit Anti-Placental lactogen I+II/Gold Conjugated antibody (bs-12940R-Gold)
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說 明 書: 100ul(10nm  15nm  35nm
100ul/2980.00元
大包裝/詢價
產品編號 bs-12940R-Gold
英文名稱 Rabbit Anti-Placental lactogen I+II/Gold Conjugated antibody
中文名稱 膠體金標記的胎盤催乳素1/2抗體
別    名 Choriomammotropin; Chorionic somatomammotropin B; Chorionic somatomammotropin hormone 2; Chorionic somatomammotropin hormone; CS 2; CS2; CSB; CSH_HUMAN; CSH1; CSH2; hCS B; HCSB; Lactogen; mPL II; mplII; Pl 2; PL; Pl2; Placental lactogen; Placental lactogen II; Prl3b1; Prolactin 3B1; prolactin family 3, subfamily b, member 1; Placental lactogen I; Placental lactogen II; rPLII.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul(10nm  15nm  35nm
研究領域 細胞生物  免疫學  發育生物學  信號轉導  生長因子和激素  內分泌病  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, )
產品應用 IEM=1:20-200 ICA=1:20-200 ChIP=1:20-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 0.4mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSH2/Placental lactogen I/II
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.02M TBS(pH8.2) with 1% BSA, 0.03% Proclin300.
保存條件 Store at 2-8 oC for 3-6 months. Avoid repeated freeze/thaw cycles.
產品介紹 background:
Placental lactogens, also referred to as chorionic somatomammotropin hormones, are protein hormones. They are produced in the mammalian placenta and are similar in structure and function to growth hormones. Together, placental lactogens and growth factors play an essential role to assure successful lactation after pregnancy. Placental lactogens also modify the metabolic state of the mother during pregnancy to supply energy to the fetus. Placental lactogen I is a member of the somatotropin/prolactin family of hormones. The proteins in this family are crucial in mammalian growth control. Placental lactogen I is expressed primarily during mid-pregnancy, and it has been reported that DNA methylation regulates its tissue expression in rats. Placental lactogen II is expressed later in pregnancy and, in mice, its secretion is regulated by the inhibitory control of GH, the concentration of which increases rapidly at the beginning of the last half of pregnancy.

Function:
Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization.

Subcellular Location:
Secreted.

Similarity:
Belongs to the somatotropin/prolactin family.

Database links:

Entrez Gene: 1442 Human

Entrez Gene: 1443 Human

Omim: 150200 Human

SwissProt: P01243 Human

Unigene: 654390 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
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