超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
亚洲国产精品va在线看黑人动漫,天天干少妇,888av视频
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-CSP/Cy5 Conjugated antibody (bs-12944R-Cy5)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-12944R-Cy5
英文名稱 Rabbit Anti-CSP/Cy5 Conjugated antibody
中文名稱 Cy5標記的半胱氨酸延伸蛋白α抗體
別    名 CLN 4; CLN4; CLN4B; CSP; cysteine string protein alpha; Cysteine string protein; DJC5; DnaJ (Hsp40) homolog subfamily C member 5; DnaJ homolog subfamily C member 5; DNAJC 5; Dnajc5; DNAJC5A; DNJC5_HUMAN; NCL.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  神經生物學  信號轉導  細胞類型標志物  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Pig, Cow, Horse, Rabbit, Sheep, Guinea Pig, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 22kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human CSP
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
Cysteine string proteins (CSPs) are synaptic vesicle-associated, secretory vesicle proteins that are involved in Ca2+-regulated exocytosis of synaptic vesicles and modulation of presynaptic transmembrane calcium fluxes in neuroendocrine and endocrine cell types. CSP contains a J-domain that binds HSP 70/HSC 70 chaperone ATPases and a membrane-targeting, palmitoylated cysteine-rich string region. CSPs may act as molecular chaperones in synapses, and mediate conformational folding of components of the vesicular exocytotic machinery. CSP is involved in the fine tuning of neurotransmission through its interaction with receptor-coupled trimeric GTP binding proteins (G proteins) and N-type Ca2+ channels. Two variants of CSP have been described: CSP1; and the 31 amino acid, C-terminally truncated isoform, CSP2. Subcellular fractionation of insulinoma cells shows CSP1 in granular fractions, while the membrane and cytosol fractions contain predominantly CSP2. The fractions also contain additional proteins, presumably CSP dimers. Furthermore, in various mammalian cell lines (including rat brain) CSP1 expression predominates CSP2 expression.

Function:
May have an important role in presynaptic function. May be involved in calcium-dependent neurotransmitter release at nerve endings.

Subunit:
Homodimer (Probable). Interacts with the chaperone complex consisting of HSC70 and SGTA (By similarity).

Subcellular Location:
Membrane. Melanosome. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.

Tissue Specificity:
Expressed in pancreas, kidney, skeletal muscle, liver, lung, placenta, brain and heart.

Post-translational modifications:
Fatty acylated. Heavily palmitoylated in the cysteine string motif.

DISEASE:
Neuronal ceroid lipofuscinosis 4B (CLN4B) [MIM:162350]: An adult-onset neuronal ceroid lipofuscinosis. Neuronal ceroid lipofuscinoses are progressive neurodegenerative, lysosomal storage diseases characterized by intracellular accumulation of autofluorescent liposomal material, and clinically by seizures, dementia, visual loss, and/or cerebral atrophy. CLN4B has no visual involvement and is characterized by seizures and other neurologic symptoms. Note=The disease is caused by mutations affecting the gene represented in this entry.

Similarity:
Contains 1 J domain.

Database links:

Entrez Gene: 80331 Human

Entrez Gene: 13002 Mouse

Entrez Gene: 79130 Rat

Omim: 611203 Human

SwissProt: Q9H3Z4 Human

SwissProt: P60904 Mouse

SwissProt: P60905 Rat

Unigene: 164419 Human

Unigene: 140761 Mouse

Unigene: 391807 Mouse

Unigene: 100120 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 国产精品99久久久久久人 | 少妇搡BBBB搡BBB搡野外 | 国产精品国产精品国产 | 性一交一乱一色一免费无遮挡 | 国产成人鲁色资源国产91色综 | 四虎海外网址 | 爽爽淫人网 | 国产精成A品人V在线播放 | 久久夜色精品国产嚕嚕亚洲av | 午夜亚洲理论片在线观看 | 免费在线看一区 | 2021年国产精品每日更新 | 婷婷久久久亚洲欧洲日产国码AV | 日本三线免费视频观看 | 午夜影院美女 | 91麻豆久久 | 日本一级大毛片a一 | 国产精品区一区二区三在线播放 | 新白娘子传奇免费50集 | 日本公妇乱淫免费视频一区三区 | 国产公开免费人成视频 | 蜜桃视频成人在线观看 | 77成人网| 麻豆wwwcom内射软件 | 中文字幕日本乱码仑区在线 | 久久只精品99品免费久23小说 | 少妇高潮久久久久久潘金莲 | 久久久久人妻一区精品性色AV | 亚洲国产欧美一区二区三区久久 | 亚洲AV无码成H人动漫无遮挡 | 亚洲国产成人私人影院tom | 欧美乱大交xxxxx春色视频 | 日韩国产中文字幕 | 日本添下边无码视频全过程 | 粉嫩av一区二区三区入口 | 狠狠插久久综合网最新章节 | 欧美精品videos另类 | 欧美日韩欧美日韩在线观看视频 | 成人午夜A片一区二区三区 av资源站最稳定的资源站 | 99插插 | 69网站在线观看 |