超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
狂野欧美性猛xxxx乱大交,精品国产午夜肉伦伦,国产成人无码精品一区在线观看
Rabbit Anti-UBR5/FITC Conjugated antibody (bs-13052R-FITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產(chǎn)品編號 bs-13052R-FITC
英文名稱 Rabbit Anti-UBR5/FITC Conjugated antibody
中文名稱 FITC標(biāo)記的E3泛素蛋白連接酶EDD抗體
別    名 4432411E13Rik; AW549941; C77315; D030042K14; DD5; E3 identified by differential display; E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase UBR5; EDD 1; EDD; EDD1; FLJ11310; HECT domain-containing 1; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; MGC57263; mKIAA0896; Progestin induced protein; Progestin-induced protein; Rat100; Ubiquitin protein ligase; Ubiquitin protein ligase E3 component n recognin 5; UBR5; UBR5_HUMAN.  
規(guī)格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  泛素  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 309kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDD
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EDD is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). May be involved in maturation and/or transcriptional regulation of mRNA. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development.

Subunit:
Binds TOPBP1. Associates with CDK9 and TFIIS/TCEA1 and forms a transcription regulatory complex made of CDK9, RNAP II, UBR5 and TFIIS/TCEA1 that can stimulate target gene transcription (e.g. gamma fibrinogen/FGG) by recruiting their promoters. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex). Interacts directly with DYRK2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed. Most abundant in testis and expressed at high levels in brain, pituitary and kidney.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 1 PABC domain.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 515582 Cow

Entrez Gene: 51366 Human

Entrez Gene: 70790 Mouse

Entrez Gene: 100157625 Pig

Entrez Gene: 117060 Rat

Omim: 608413 Human

SwissProt: O95071 Human

SwissProt: Q80TP3 Mouse

SwissProt: Q62671 Rat

Unigene: 492445 Human

Unigene: 476840 Mouse

Unigene: 54812 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過國際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網(wǎng)安備110107000727號
主站蜘蛛池模板: 一级做a爰片性色毛片 | 免费成人91| 东京热无码AV在线 | 97久久人人超碰超碰窝窝 | 日韩有码在线观看 | av在线亚洲男人的天堂 | 蘑菇视频黄色 | free性丰满白嫩白嫩的hd | 国产在线观看免费网站 | aaaa成人| 国产精品久久久福利 | 日本在线观看中文自拍 | 色视频网站免费观看 | 国产在线高清视频无码不卡互動交流 | 欧美人做人爱a全程免费 | 在线免费小视频 | 国产网友愉拍精品视频手机人 | 国产精品一区二区三区在线 | www.youjizz.com最新 | 少妇人妻H好紧 | 日本xxxx视频| 中文字幕天天躁日日躁狠狠躁 | 91成人在线免费 | 国产午夜无码片在线观看 | 欧美一级无毛 | 亚洲AV永久无码3D动漫在线观看 | 91在线影院 | 日韩久久久久久久久久久久 | 亚洲美女在线播放 | 国产毛片久久久久久蜜臂媒 | 成人国产在线视频 | 精品二区 | 欧美视频自拍 | 少妇大叫太大太爽受不了在线观看 | 国产高清在线精品一本大道 | 欧美aaa一级片 | 精品欧美在线观看 | 天天爱天天做天天爽2021 | 久碰香蕉线视频在线观看视频 | 乱人伦中文字幕无码 | 狠狠躁夜夜躁人人爽天天开心婷婷 |