超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關(guān)注公眾號(hào)           掃碼咨詢技術(shù)支持           掃碼咨詢技術(shù)服務(wù)
  
客服熱線:400-901-9800  客服QQ:4009019800  技術(shù)答疑  技術(shù)支持  質(zhì)量反饋  關(guān)于我們  聯(lián)系我們
国产精品自拍500,亚洲一区在线免费观看,91激情视频在线
Rabbit Anti-UBR5/PE-Cy5 Conjugated antibody (bs-13052R-PE-Cy5)
訂購(gòu)熱線:400-901-9800
訂購(gòu)郵箱:sales@bioss.com.cn
訂購(gòu)QQ:  400-901-9800
技術(shù)支持:techsupport@bioss.com.cn
說(shuō) 明 書(shū): 100ul  
100ul/2980.00元
大包裝/詢價(jià)
產(chǎn)品編號(hào) bs-13052R-PE-Cy5
英文名稱(chēng) Rabbit Anti-UBR5/PE-Cy5 Conjugated antibody
中文名稱(chēng) PE-Cy5標(biāo)記的E3泛素蛋白連接酶EDD抗體
別    名 4432411E13Rik; AW549941; C77315; D030042K14; DD5; E3 identified by differential display; E3 ubiquitin protein ligase, HECT domain containing, 1; E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase UBR5; EDD 1; EDD; EDD1; FLJ11310; HECT domain-containing 1; hHYD; HYD; Hyperplastic discs protein homolog; KIAA0896; MGC57263; mKIAA0896; Progestin induced protein; Progestin-induced protein; Rat100; Ubiquitin protein ligase; Ubiquitin protein ligase E3 component n recognin 5; UBR5; UBR5_HUMAN.  
規(guī)格價(jià)格 100ul/2980元 購(gòu)買(mǎi)        大包裝/詢價(jià)
說(shuō) 明 書(shū) 100ul  
研究領(lǐng)域 細(xì)胞生物  表觀遺傳學(xué)  泛素  
抗體來(lái)源 Rabbit
克隆類(lèi)型 Polyclonal
交叉反應(yīng) Mouse,  (predicted: Human, Rat, Chicken, Dog, Pig, Horse, Sheep, )
產(chǎn)品應(yīng)用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 309kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human EDD
亞    型 IgG
純化方法 affinity purified by Protein A
儲(chǔ) 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹 background:
EDD is a progestin-regulated gene that was isolated from T-47D human breast cancer cells. Based on sequence homology, EDD appears to be a human homolog of the Drosophila hyperplastic discs (hyd) gene, a tumor suppressor gene that is required for control of imaginal disc growth. EDD contains a HECT domain in the carboxy terminus. HECT domain-containing proteins function as ubiquitin-protein ligases, or E3 enzymes. EDD has been shown to bind to ubiquitin, and like other HECT family proteins, may function as an E3 ubiquitin-protein ligase.

Function:
E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific amino-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). May be involved in maturation and/or transcriptional regulation of mRNA. May play a role in control of cell cycle progression. May have tumor suppressor function. Regulates DNA topoisomerase II binding protein (TopBP1) in the DNA damage response. Plays an essential role in extraembryonic development.

Subunit:
Binds TOPBP1. Associates with CDK9 and TFIIS/TCEA1 and forms a transcription regulatory complex made of CDK9, RNAP II, UBR5 and TFIIS/TCEA1 that can stimulate target gene transcription (e.g. gamma fibrinogen/FGG) by recruiting their promoters. Associates with the E3 ligase complex containing DYRK2, EDD/UBR5, DDB1 and VPRBP proteins (EDVP complex). Interacts directly with DYRK2.

Subcellular Location:
Nucleus.

Tissue Specificity:
Widely expressed. Most abundant in testis and expressed at high levels in brain, pituitary and kidney.

Post-translational modifications:
Phosphorylated upon DNA damage, probably by ATM or ATR.

Similarity:
Contains 1 HECT (E6AP-type E3 ubiquitin-protein ligase) domain.
Contains 1 PABC domain.
Contains 1 UBR-type zinc finger.

Database links:

Entrez Gene: 515582 Cow

Entrez Gene: 51366 Human

Entrez Gene: 70790 Mouse

Entrez Gene: 100157625 Pig

Entrez Gene: 117060 Rat

Omim: 608413 Human

SwissProt: O95071 Human

SwissProt: Q80TP3 Mouse

SwissProt: Q62671 Rat

Unigene: 492445 Human

Unigene: 476840 Mouse

Unigene: 54812 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權(quán)所有 2004-2026 www.ggggww.cn 北京博奧森生物技術(shù)有限公司
通過(guò)國(guó)際質(zhì)量管理體系ISO 9001:2015 GB/T 19001-2016    證書(shū)編號(hào): 00124Q34771R2M/1100
通過(guò)國(guó)際醫(yī)療器械-質(zhì)量管理體系ISO 13485:2016 GB/T 42061-2022    證書(shū)編號(hào): CQC24QY10047R0M/1100
京ICP備05066980號(hào)-1         京公網(wǎng)安備110107000727號(hào)
主站蜘蛛池模板: 日韩国产中文字幕 | 国产内射大片99 | 视频免费观看在线 | 无码字幕av一区二区三区 | 另类小说一区 | 日本三级全黄三级a | 网曝门国产一区二区三区四区 | 久久精品视频一区二区三区 | 少妇被猛男粗大的猛进出 | 性bbbbbxxxxxzzzzz | 亚洲av无码色情第一综合网 | 日韩免费区 | 巨乳一区| 亚洲综合熟女久久久30p | 欧美亚洲日韩在线综合 | 中国熟女高潮视频 | 日日噜噜噜噜夜夜爽 | 免费看日本黄色片 | AV无码专区亚洲AV极速版 | 亚洲国产一区二区三区在线观看 | 一级免费黄色毛片 | 99久久免费精品国产男女高不卡 | 少妇人妻偷人精品无码视频新浪 | 色播久久人人爽人人爽人人片av | 成片人免费观看一级A片 | 久久久久人妻一区精品性色AV | 精品国产二区在线 | 欧美特黄一级视频 | 久久99精品久久久久久无毒不卡8 | 在线偷窥 | 第一次破處在线国语视频播放 | 国产一区二区看久久 | 天天摸天天碰天天添 | www.日韩com| 欧美人体一区二区视频 | 国偷av久久久久久 | 国产高清在线精品二区 | 无码AV无码一区二区 | 国产高潮好爽受不了了夜夜做 | 国内精品A片XXX久久久 | 国产精自产拍久久久久久蜜 |