超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
7色av,久久69国产一区二区蜜臀,亚洲色无码中文字幕
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Ephexin-1 (Tyr179)/RBITC Conjugated antibody (bs-13084R-RBITC)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13084R-RBITC
英文名稱 Rabbit Anti-phospho-Ephexin-1 (Tyr179)/RBITC Conjugated antibody
中文名稱 羅丹明(RBITC)標記的磷酸化神經細胞鳥苷酸置換因子Ephexin1抗體
別    名 Ephexin-1 (phospho Y179); p-Ephexin-1 (phospho Y179); ARHGEF27; Eph-interacting exchange protein; EPHEXIN; Ephexin 1; Neuronal guanine nucleotide exchange factor; Ngef; NGEF_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  神經生物學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Ephexin-1 around the phosphorylation site of Tyr179
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.

Function:
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension.

Subunit:
Interacts with CDK5R1 and EPHA4; activated by EPHA4 through the CDK5 kinase.

Subcellular Location:
Cytoplasm. Membrane. Cell projection, growth cone. Associated with membranes. Localizes to axonal growth cones.

Tissue Specificity:
Highly expressed in brain specifically in caudate nucleus and to a lower extent in amygdala and hippocampus. Also detected in lung.

Post-translational modifications:
Src-dependent phosphorylation at Tyr-179 upon EPHA4 activation increases the guanine exchange factor activity toward RHOA.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: Q8N5V2.2

Database links:

Entrez Gene: 25791 Human

Entrez Gene: 53972 Mouse

Entrez Gene: 246217 Rat

Entrez Gene: 424744 Chicken

Omim: 605991 Human

SwissProt: Q8N5V2 Human

SwissProt: Q8CHT1 Mouse

SwissProt: Q5BKC9 Rat

Unigene: 97316 Human

Unigene: 435439 Mouse

Unigene: 20670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: av中文无码乱人伦 | 欧美疯狂xxx免费视频 | 亚洲激精日韩激精欧美精品 | 亚洲免费视频一区 | 免费无码aⅴ免费中文字幕 91杏吧在线观看 | 草久视频 | 18高清免费a级毛片av | 91丨九色丨国产在线观看 | 91av国产在线视频 | 国产精品视频精品 | 成人免费ssss片 | 成人在线欧美 | 国产日韩在线看 | 欧美性猛交xxxx乱大交久久 | 亚洲日韩欧美一区二区三区 | 亚洲天堂久久新 | 国产精品综合二区 | 日本人在线看片免费观看 | 日韩欧美一区二区三区 | 国产午夜免费视频 | 久久er精品 | 中文日韩欧美 | 91久久色 | 亚洲一区综合 | 人妻激情偷乱视频一区二区三区 | 欧美一级黄色免费看 | 性欧美精品高清 | 深夜A级毛片视频免费 | 69日本xxxxxxxxx59 亚洲AV综合色区无码一二三区 | 欧美成人免费一级人片100 | 黄色片哪里可以看 | 国产成人无码A在线观看不卡 | 精品国产人免费观看成人片 | 日本男女爱爱视频 | 中文字幕日韩精品免费看 | 亚洲精品一卡二卡三卡四卡2021 | 在线观看午夜看亚太视频 | 把护士强奷到舒服的动态图 | 最新韩日剧情片在线免费观看 | 九色丨porny 无码专区视频中文字幕 | 少妇高潮太爽了在线观看欧美 |