超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
国产成人精品无码一区二区蜜柚,免费爱爱视频网站,欧美黄色免费在线观看
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-phospho-Ephexin-1 (Tyr179)/PE-Cy7 Conjugated antibody (bs-13084R-PE-Cy7)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13084R-PE-Cy7
英文名稱 Rabbit Anti-phospho-Ephexin-1 (Tyr179)/PE-Cy7 Conjugated antibody
中文名稱 PE-Cy7標記的磷酸化神經細胞鳥苷酸置換因子Ephexin1抗體
別    名 Ephexin-1 (phospho Y179); p-Ephexin-1 (phospho Y179); ARHGEF27; Eph-interacting exchange protein; EPHEXIN; Ephexin 1; Neuronal guanine nucleotide exchange factor; Ngef; NGEF_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
產品類型 磷酸化抗體 
研究領域 細胞生物  神經生物學  信號轉導  G蛋白偶聯受體  G蛋白信號  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 (predicted: Human, Mouse, Rat, Chicken, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 82kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthesised phosphopeptide derived from human Ephexin-1 around the phosphorylation site of Tyr179
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
EPHEXIN is a 710 amino acid protein that localizes to both the membrane and the cytoplasm and contains one SH3 domain, one PH domain and one DH domain. Expressed at high levels in brain and present at lower levels in lung tissue, EPHEXIN interacts with EphA4 and functions as a guanine nucleotide exchange factor (GEF) that is capable of activating Rho A, Rac 1 and Cdc42 and is thought to play a role in axon guidance and growth cone collapse. EPHEXIN is subject to Src-dependent phosphorylation, an event that increases the GEF activity of EPHEXIN toward Rho A. Human EPHEXIN, which exists as multiple alternatively spliced isoforms, shares a high degree of sequence homology with its mouse counterpart, suggesting a conserved role between species.

Function:
Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1-and CDC42-stimulated growth cone extension.

Subunit:
Interacts with CDK5R1 and EPHA4; activated by EPHA4 through the CDK5 kinase.

Subcellular Location:
Cytoplasm. Membrane. Cell projection, growth cone. Associated with membranes. Localizes to axonal growth cones.

Tissue Specificity:
Highly expressed in brain specifically in caudate nucleus and to a lower extent in amygdala and hippocampus. Also detected in lung.

Post-translational modifications:
Src-dependent phosphorylation at Tyr-179 upon EPHA4 activation increases the guanine exchange factor activity toward RHOA.

Similarity:
Contains 1 DH (DBL-homology) domain.
Contains 1 PH domain.
Contains 1 SH3 domain.
Database links : UniProtKB/Swiss-Prot: Q8N5V2.2

Database links:

Entrez Gene: 25791 Human

Entrez Gene: 53972 Mouse

Entrez Gene: 246217 Rat

Entrez Gene: 424744 Chicken

Omim: 605991 Human

SwissProt: Q8N5V2 Human

SwissProt: Q8CHT1 Mouse

SwissProt: Q5BKC9 Rat

Unigene: 97316 Human

Unigene: 435439 Mouse

Unigene: 20670 Rat



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 永久免费av无码不卡在线观看 | 久久麻豆精品 | av中文字幕免费在线观看 | jiujiure精品视频播放 | 国产成人亚洲精品另类动态 | 国产美女自卫慰视频福利 | 777米奇色8888狠狠俺去了 | 欧美亚洲在线 | av在线天天 | 曰韩不卡视频 | 狠狠躁天天躁夜夜添人人 | 18禁超污无遮挡无码免费动态图 | 四虎海外网址 | 精品国产人免费观看成人片 | 国产精品国产三级国产aⅴ中文 | 国产女女做受ⅹxx高潮 | 日韩国产成人在线 | 久操麻豆| 日韩08精品 | 337P日本欧洲亚洲高清鲁鲁 | 一级做a爰大片免费 | 亚洲国产国语自产精品 | 国产精品人妖 | 欧美日韩一区精品 | 欧美精品在线一区二区三区 | 国产精品免费一区二区三区 | 亲亲草在线视频 | 国产999精品久久久久久 | 中文字幕av伊人av无码av | 中文字幕第66页 | 国产在线无码视频一区二区三区 | 学生妹av | 无遮挡亲胸捏胸免费视频 | 国产三级精品三级在线专区 | 在线播放网址亚洲 | 手机在线视频福利 | 91精品久久久久久久久久久 | 国产免费又黄又爽又色毛 | 四虎成人精品国产永久免费 | 亚洲久久色| 四虎海外网址 |