超碰97自拍_久久99久久98精品免观看软件_在线亚洲一区_九九视频这里只有精品_国产精品一区二区欧美视频_精品国产区一区

掃碼關注公眾號           掃碼咨詢技術支持           掃碼咨詢技術服務
  
客服熱線:400-901-9800  客服QQ:4009019800  技術答疑  技術支持  質量反饋  關于我們  聯系我們
久久人人97超碰com,5060国产午夜无码专区,国产激情无码一区二区三区
首頁 > 產品中心 > 標記一抗 > 產品信息
Rabbit Anti-FKBP10/BF555 Conjugated antibody (bs-13175R-BF555)
訂購熱線:400-901-9800
訂購郵箱:sales@bioss.com.cn
訂購QQ:  400-901-9800
技術支持:techsupport@bioss.com.cn
說 明 書: 100ul  
100ul/2980.00元
大包裝/詢價
產品編號 bs-13175R-BF555
英文名稱 Rabbit Anti-FKBP10/BF555 Conjugated antibody
中文名稱 BF555標記的肽基脯氨酰順反異構酶FKBP10抗體
別    名 65 kDa FK506 binding protein; FK506 binding protein 10 65 kDa; FK506 binding protein 10; FKBP 10; FKBP 65; hFKBP 65; Immunophilin FKBP65; Peptidyl prolyl cis trans isomerase. PPIase; Rotamase; FKB10_HUMAN.  
規格價格 100ul/2980元 購買        大包裝/詢價
說 明 書 100ul  
研究領域 細胞生物  信號轉導  轉運蛋白  結合蛋白  
抗體來源 Rabbit
克隆類型 Polyclonal
交叉反應 Human, Mouse, Rat,  (predicted: Dog, Pig, Cow, Horse, Sheep, )
產品應用 ICC=1:50-200 IF=1:50-200 
not yet tested in other applications.
optimal dilutions/concentrations should be determined by the end user.
分 子 量 61kDa
性    狀 Lyophilized or Liquid
濃    度 1mg/ml
免 疫 原 KLH conjugated synthetic peptide derived from human FKBP10
亞    型 IgG
純化方法 affinity purified by Protein A
儲 存 液 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol
保存條件 Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產品介紹 background:
The immunophilins are a highly conserved family of cis-trans peptidyl-prolyl isomerases that bind to and mediate the effects of immunosuppressive drugs, such as cyclosporin, FK506 and rapamycin. Immunophilins have also been implicated in protein folding and trafficking within the endoplasmic reticulum (ER). FKBP10 (FK506-binding protein 10), also known as peptidyl-prolyl cis-trans isomerase, PPIase, Rotamase, 65kDa FK506-binding protein or FKBP65, is a 582 amino acid immunophilin localized to the ER lumen and found in many tissues including heart, spleen, brain, testis and lung. FKBP10 contains two EF-hand calcium-binding domains and four PPIase FKBP-type domains, suggesting an enzymatic role in protein folding by catalyzing the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. FKBP10 also acts as a receptor for the immunosuppressants FK506 and rapamycin, which inhibit FKBP10 activity. FKBP10 is thought to interact with the Raf-1/HSP 90 heterocomplex during signal transduction processes, and may associate with elastin during elastin protein folding and transport. With a valine-24 addition to human FKBP10, human and mouse FKBP10 are almost identical.

Function:
FKBP10 (FK506 binding protein 10) belongs to the FKBP type peptidyl-prolyl cis/trans isomerase (PPIase) family. PPIases accelerate the folding of proteins during protein synthesis, acting as molecular chaperones. FKBP10 is located in the endoplasmic reticulum (ER) and is thought to play a role in the folding and trafficking of secretory proteins.

Subcellular Location:
Endoplasmic reticulum.

Post-translational modifications:
Glycosylated and phosphorylated.

DISEASE:
Defects in FKBP10 are the cause of osteogenesis imperfecta type 6 (OI6) [MIM:610968]. OI6 is a moderate to severe, autosomal recessive form of osteogenesis imperfecta characterized by increased serum alkaline phosphatase levels and bone histology exhibiting a fish scale-like lamellar pattern. Osteogenesis imperfecta defines a group of connective tissue disorders characterized by bone fragility and low bone mass.

Similarity:
Contains 2 EF-hand domains.
Contains 4 PPIase FKBP-type domains.

Database links:

Entrez Gene: 60681 Human

Omim: 607063 Human

SwissProt: Q96AY3 Human

Unigene: 463035 Human



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.
版權所有 2004-2026 www.ggggww.cn 北京博奧森生物技術有限公司
通過國際質量管理體系ISO 9001:2015 GB/T 19001-2016    證書編號: 00124Q34771R2M/1100
通過國際醫療器械-質量管理體系ISO 13485:2016 GB/T 42061-2022    證書編號: CQC24QY10047R0M/1100
京ICP備05066980號-1         京公網安備110107000727號
主站蜘蛛池模板: 少妇仑乱A毛片无码 | 久久精品国产99久久6动漫亮点 | 国产做a爰片久久毛片a片 | 国产成AV人在线观看天堂无码 | 午夜视频1000 | 国产日韩精品一区二区三区在线 | 久久se精品一区精品二区 | 国产精品亚洲аv久久亚瑟桃花 | 91蜜桃臀久久一区二区 | 国产精品午夜一区 | 国产视频一区二区 | 中文字幕av久久人妻蜜桃臀 | 欧日韩毛片 | 99久久国产综合精麻豆 | 一区二区三区欧美视频 | 波多野结衣在线观看中文字幕 | 女同免费毛片在线播放 | 午夜视频中文字幕 | 三男一女吃奶添下面 | 精品中文字幕一区 | 日本三级无码中文字幕 | av中文无码乱人伦 | 亚洲∧V久久久无码精品 | 日日夜夜天天射 | 日韩观看 | 久久成人在线观看 | 给我看免费播放片的视频 | 男生戳美女两腿中间那个视频 | 校园都市经典激情另类 | 国产成a人亚洲精品无码久久网 | 超碰9在线 | 99久久99久久免费精品小说 | 又粗又硬又黄又爽的免费视频 | 99久久人妻无码精品系列蜜桃 | 国产精品草草在线观看 | YY111111少妇无码理论片 | 亚洲综合欧美日韩狠狠色 | 久热2020 | 色欲天天天综合网 | 国产亚洲第一区 | 狠狠狼鲁亚洲综合网 |